66040-43-5Relevant articles and documents
Novel potent anticonvulsant agent containing a tetrahydroisoquinoline skeleton
Gitto, Rosaria,Caruso, Roberta,Pagano, Benedetta,De Luca, Laura,Citraro, Rita,Russo, Emilio,De Sarro, Giovambattista,Chimirri, Alba
, p. 5618 - 5622 (2007/10/03)
In our studies on the development of new anticonvulsants, we planned the synthesis of N-substituted 1,2,3,4-tetrahydroisoquinolines to explore the structure-activity relationships. All derivatives were evaluated against audiogenic seizures in DBA/2 mice,