6607-46-1 Usage
Description
((E)-1,2-DIBROMO-VINYL)-BENZENE, also known as 1,2-dibromo-2-phenylethene, is a chemical compound with the molecular formula C8H6Br2. It is a colorless to yellow liquid at room temperature and is insoluble in water. ((E)-1,2-DIBROMO-VINYL)-BENZENE is commonly used in organic synthesis and serves as an intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds. Additionally, it is utilized as a building block in the creation of polymers and other industrial materials. Due to its toxic nature and potential to cause irritation to the skin, eyes, and respiratory system, it should be handled with caution.
Uses
Used in Organic Synthesis:
((E)-1,2-DIBROMO-VINYL)-BENZENE is used as a key intermediate in organic synthesis for the production of various organic compounds. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis of a wide range of products.
Used in Pharmaceutical Production:
In the pharmaceutical industry, ((E)-1,2-DIBROMO-VINYL)-BENZENE is used as an intermediate in the synthesis of various drugs. Its reactivity and structural properties enable the development of new pharmaceutical agents with potential therapeutic applications.
Used in Agrochemical Production:
((E)-1,2-DIBROMO-VINYL)-BENZENE is also utilized in the agrochemical sector as an intermediate for the synthesis of pesticides and other agricultural chemicals. Its role in the production of these compounds contributes to the development of effective solutions for crop protection and management.
Used in Polymer Production:
In the polymer industry, ((E)-1,2-DIBROMO-VINYL)-BENZENE serves as a building block for the creation of various polymers and industrial materials. Its incorporation into these materials can enhance their properties, such as strength, durability, and resistance to environmental factors.
Used in Other Industrial Applications:
Beyond the aforementioned industries, ((E)-1,2-DIBROMO-VINYL)-BENZENE finds use in other areas, including the production of dyes, fragrances, and other specialty chemicals. Its versatility and reactivity make it a valuable component in a diverse range of industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 6607-46-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,0 and 7 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6607-46:
(6*6)+(5*6)+(4*0)+(3*7)+(2*4)+(1*6)=101
101 % 10 = 1
So 6607-46-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H6Br2/c9-6-8(10)7-4-2-1-3-5-7/h1-6H/b8-6+
6607-46-1Relevant articles and documents
TEMPO-Regulated Regio- and Stereoselective Cross-Dihalogenation with Dual Electrophilic X+ Reagents
Kong, Yi,Cao, Tongxiang,Zhu, Shifa
supporting information, p. 3004 - 3010 (2021/08/23)
A TEMPO catalyzed cross-dihalogenation reaction was established via redox-regulation of the otherwise complex system of dual electrophilic X+ reagents. Formally, the ICl, BrCl, I2 and Br2 were generated in-situ, which enabled high regio- or stereoselective access to a myriad of iodochlorination, bromochlorination and homo-dihalogenation products with a wide spectrum of functionalities. With its mild conditions and operational simplicity, this method could enable wide applications in organic synthesis, which was exemplified by divergent synthesis of two pharmaceuticals. Detailed mechanistic investigations via radical clock reaction, pinacol ring expansion and Hammett experiments were conducted, which confirmed the intermediacy of halonium ion. In addition, a dynamic catalytic model based on the versatile catalytic role of TEMPO was proposed to explain the selective outcomes.
Electrochemical synthesis of α,α-dihaloacetophenones from terminal alkyne derivatives
Li, Zhibin,Sun, Qi,Qian, Peng,Hu, Kangfei,Zha, Zhenggen,Wang, Zhiyong
supporting information, p. 1855 - 1858 (2020/03/10)
By virtue of electrochemistry, a series of α,α-dihaloacetophenones were easily obtained with good to excellent yields. This electrochemical procedure was taken in a divided cell with constant current in aqueous media. The reaction can be carried out smoothly at room temperature under metal and oxidant free condition, which provides an eco-friendly synthesis for the α,α-dihaloacetophenone derivatives.
AuIII-Catalyzed Formation of α-Halomethyl Ketones from Terminal Alkynes
Xing, Yalan,Zhang, Ming,Ciccarelli, Sarah,Lee, John,Catano, Bryant
supporting information, p. 781 - 785 (2017/02/15)
A AuIII-catalyzed synthesis of α-halomethyl ketones from terminal alkynes was developed. This approach features excellent functional group compatibility and good yields for both aromatic and aliphatic terminal alkynes. The resulting α-halomethyl ketones were used to prepare heterocyclic indolizine structures. The plausible mechanism of the one-pot reaction is proposed.
