66078-55-5Relevant articles and documents
CONVERSION OF NITRILES TO THIOAMIDES UNDER THE ACTION OF THE BINARY THIONYLATING SYSTEM PHOSPHORUS DITHIOACID-ALCOHOL
Zabirov, N. G.,Shamsevaleev, F. M.,Cherkasov, R. A.
, p. 56 - 63 (2007/10/02)
Binary systems of phosphorus dithioacid-methanol and phosphorus pentasulfide-methanol are effective hydrosulfonating systems for the conversion of aromatic nitriles to the corresponding primary thioamides.In ternary systems nitrile-phosphorus dithioacid-alcohol from one to four parallel processes can occur.The structure of the phosphorus dithioacids has little effect, whereas the structures of the nitrile and alcohol substantially influence both the rate of the processes and the possible pathway.The reactivity of alcohols in these reactions drops with increasing volume of the hydrocarbon radical.
THE REACTION OF NITRILES WITH O,O-DIALKYL-DITHIOPHOSPHORIC ACIDS
Yousif, N. M.
, p. 4599 - 4604 (2007/10/02)
Nitriles react with dialkyldithiophosphoric acids 2a-c to give a mixture of corresponding thioamides and O,O-dialkyl-N-thioacetyl-phosphoroamidothioates 3a-e.The structure of compounds 3 are elucidated chemically and from electronic spectra.The yield of thioamides are improved from the reaction of nitriles with compound 2b in presence of water.Mechanistic consideration on the formation of the products are discussed.
