662110-21-6

Basic information

• Product Name: (Z)-methyl 2-[(4-chlorophenyl)(methanesulfonyloxy)methyl]-3-nitroacrylate
• Synonyms: (Z)-methyl 2-[(4-chlorophenyl)(methanesulfonyloxy)methyl]-3-nitroacrylate
• CAS NO: 662110-21-6
• Molecular Weight: 349.749
• Mol File: 662110-21-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-methyl 2-[(4-chlorophenyl)(methanesulfonyloxy)methyl]-3-nitroacrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-methyl 2-[(4-chlorophenyl)(methanesulfonyloxy)methyl]-3-nitroacrylate(662110-21-6)
• EPA Substance Registry System: (Z)-methyl 2-[(4-chlorophenyl)(methanesulfonyloxy)methyl]-3-nitroacrylate(662110-21-6)

Safety Data

• Hazardous Substances Data: 662110-21-6(Hazardous Substances Data)

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 662110-16-9 methyl 3-(4-chlorophenyl)-2,3-dihydroxy-2-nitromethylpropionate 
• 131469-67-5 methyl 2-[1-hydroxy-1-(4-chlorophenyl)methyl]acrylate 

Downstream Products

• 49678-54-8 methyl (E)-2-cyano-3-(4-chlorophenyl)-2-propenoate 

Relevant articles and documents

NaNO2-ceric ammonium nitrate mediated conversion of acrylic esters and Baylis-Hillman derived acrylic esters into corresponding β-nitro acrylic esters

A variety of acrylic esters, including those derived from Baylis-Hillman reactions, react with NaNO2-ceric ammonium nitrate to form the corresponding β-nitro alcohols 2 and 5 whose dehydration, via their mesylates, leads to β-nitro acrylic esters, in good to excellent yields. Further, β-nitro acrylic esters containing a mesylate group 6, obtained from the Baylis-Hillman products, react with NaN3 to form 2-cyano-3-substituted acrylic esters 10 in excellent yields.