662111-36-6

Basic information

• Product Name: 2(3H)-Benzothiazolone, 7-[(1R)-2-bromo-1-hydroxyethyl]-4-(phenylmethoxy)-
• CAS NO: 662111-36-6
• Molecular Formula: C16H14BrNO3S
• Molecular Weight: 380.262
• Mol File: 662111-36-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2(3H)-Benzothiazolone, 7-[(1R)-2-bromo-1-hydroxyethyl]-4-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Benzothiazolone, 7-[(1R)-2-bromo-1-hydroxyethyl]-4-(phenylmethoxy)-(662111-36-6)
• EPA Substance Registry System: 2(3H)-Benzothiazolone, 7-[(1R)-2-bromo-1-hydroxyethyl]-4-(phenylmethoxy)-(662111-36-6)

Safety Data

• Hazardous Substances Data: 662111-36-6(Hazardous Substances Data)

Upstream product

• 662111-35-5 4-(benzyloxy)-7-(bromoacetyl)-1,3-benzothiazol-2(3H)-one 
• 112022-83-0 (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole 
• 80567-66-4 4-methoxy-1,3-benzothiazol-2(3H)-one 
• 662111-32-2 7-acetyl-4-methoxy-1,3-benzothiazol-2(3H)-one 
• 662111-33-3 7-acetyl-4-hydroxy-1,3-benzothiazol-2(3H)-one 
• 662111-34-4 7-acetyl-4-(benzyloxy)-1,3-benzothiazol-2(3H)-one 

Downstream Products

• 948894-43-7 4-(benzyloxy)-7-{(1R)-1-hydroxy-2-[({1-[2-(2-phenylethoxy)ethyl]piperidin-4-yl}methyl)amino]ethyl}-1,3-benzothiazol-2(3H)-one 
• 928627-62-7 7-[(1R)-2-azido-1-hydroxyethyl]-4-(benzyloxy)-1,3-benzothiazol-2(3H)-one 
• 662111-37-7 4-(benzyloxy)-7-{(1R)-2-bromo-1-[tetrahydro-2H-pyran-2-yloxy]ethyl}-1,3-benzothiazol-2(3H)-one 

Relevant articles and documents

Design driven HtL: The discovery and synthesis of new high efficacy β2-agonists

The design and synthesis of a new series of high efficacy β2-agonists devoid of the key benzylic alcohol present in previously described highly efficacious β2-agonists is reported. A hypothesis for the unprecedented level of efficacy is proposed based on considerations of β2-adrenoceptor crystal structure, other biophysical data and modeling studies.

MEDICINAL COMPOUNDS

The present invention concerns compounds of formula (I) and salts, solvates, and physiologically functional derivatives thereof, wherein: R1 is hydrogen or -XSO2NR6R7; R2 and R3 are indepen