66232-40-4

Basic information

• Product Name: Benzoic acid, 2-[(chloroacetyl)amino]-6-methyl-
• CAS NO: 66232-40-4
• Molecular Formula: C10H10ClNO3
• Molecular Weight: 227.647
• Mol File: 66232-40-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-[(chloroacetyl)amino]-6-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-[(chloroacetyl)amino]-6-methyl-(66232-40-4)
• EPA Substance Registry System: Benzoic acid, 2-[(chloroacetyl)amino]-6-methyl-(66232-40-4)

Safety Data

• Hazardous Substances Data: 66232-40-4(Hazardous Substances Data)

Upstream product

• 4389-50-8 2-amino-6-methylbenzoic acid 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 202715-64-8 2-Methyl-6-(2-phenylamino-acetylamino)-benzoic acid 
• 1333248-15-9 3-(2-ethoxyphenyl)-2-((4-(furan-2-carbonyl)piperazin-1-yl)methyl)-5-methylquinazolin-4(3H)-one 
• 1412898-10-2 2-(6-amino-8-benzylaminopurin-9-ylmethyl)-3-(2-(trifluoromethyl)phenyl)-5-methyl-3H-quinazolin-4-one 
• 371242-69-2 2-(6-aminopurin-9-ylmethyl)-5-methyl-3-o-tolyl-3H-quinazolin-4-one 
• 371243-42-4 2-(6-aminopurin-7-ylmethyl)-3-(o-tolyl)-5-(methyl)-3H-quinazolin-4-one 
• 1412898-26-0 2-(6-aminopurin-9-ylmethyl)-3-(4-trifluoromethylphenyl)-5-methyl-3H-quinazolin-4-one 
• 1412898-25-9 2-(6-aminopurin-9-ylmethyl)-3-(4-trifluoromethoxyphenyl)-5-methyl-3H-quinazolin-4-one 

Relevant articles and documents

SUBSTITUTED FUSED PYRIMIDINONE COMPOUNDS

Provided herein are novel fused pyrimidinone derivatives of Formula (I) and synthetic intermediates that are useful in preparing the compounds of formula (I). Further provided herein is a method for preparation of a compound of formula (I) or intermediate

One-pot multicomponent synthesis of medicinally important purine quinazolinone derivatives

Herein, a protocol that involves microwave-assisted, multicomponent one-pot synthetic strategy for the construction of the medicinally important purine quinazolinone scaffold is reported. A series of compounds are prepared by cyclization and condensation

Synthesis and antitumor activity of fused quinoline derivatives. V. Methylindolo[3,2-b]quinolines

Indolo[3,2-b]quinoline derivatives (1b-i) with a methyl group at each possible position have been synthesized. The 1-methyl (1b) and 9-methyl (1i) derivatives were inactive, but the 3-methyl (1d), 4-methyl (1e), and 6- methyl (1f) derivatives exhibited high treatment/control (T/C) value and cure rates against leukemia P388 in mice. These results indicated that modification of indolo[3,2-b]quinoline derivatives at 3, 4, and 6 positions may be useful approach for lead optimization.