662722-99-8

Basic information

• Product Name: 4-Thiazolecarboxylic acid, 2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinyl]-4,5-dihydro-, methyl ester, (4R)-
• CAS NO: 662722-99-8
• Molecular Formula: C14H22N2O4S
• Molecular Weight: 314.406
• Mol File: 662722-99-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Thiazolecarboxylic acid, 2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinyl]-4,5-dihydro-, methyl ester, (4R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Thiazolecarboxylic acid, 2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinyl]-4,5-dihydro-, methyl ester, (4R)-(662722-99-8)
• EPA Substance Registry System: 4-Thiazolecarboxylic acid, 2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinyl]-4,5-dihydro-, methyl ester, (4R)-(662722-99-8)

Safety Data

• Hazardous Substances Data: 662722-99-8(Hazardous Substances Data)

Upstream product

• 35150-07-3 (S)-tert-butyl 2-carbamoylpyrrolidine-1-carboxylate 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 18598-63-5 L-cysteine methyl ester hydrochloride 
• 228244-04-0 tert-butyl (2S)-2-cyanopyrrolidine-1-carboxylate 

Relevant articles and documents

Synthetic Studies on Alotamide A: Construction of N-Demethylalotamide A

Several approaches to the synthesis of cyclodepsipeptide natural product alotamide A are described, eventually affording a very advanced N-demethylated analogue of the targeted natural product. The difficulties found in our endeavors on the synthesis of alotamide A have allowed us to gather some valuable information regarding the most convenient synthetic step for each key transformation. The intramolecular Csp2?Csp2 Stille cross-coupling and the macrolactam formation were found to be reliable protocols for the final construction of the alotamide A skeleton.