66280-25-9 Usage
Uses
Gomisin J is a promising drug for anti-ovarian cancer utilization. Also, it exhibits strong inhibition towards the glucuronidation of SN-8.
Check Digit Verification of cas no
The CAS Registry Mumber 66280-25-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,2,8 and 0 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 66280-25:
(7*6)+(6*6)+(5*2)+(4*8)+(3*0)+(2*2)+(1*5)=129
129 % 10 = 9
So 66280-25-9 is a valid CAS Registry Number.
InChI:InChI=1/C22H28O6/c1-11-7-13-9-15(23)19(25-3)21(27-5)17(13)18-14(8-12(11)2)10-16(24)20(26-4)22(18)28-6/h9-12,23-24H,7-8H2,1-6H3/t11-,12+
66280-25-9Relevant articles and documents
Total Syntheses of the Lignans Isolated from Schisandra Chinensis
Tanaka, Masahide,Ohshima, Toshihiro,Mitsuhashi, Hiroshi,Maruno, Masao,Wakamatsu, Takeshi
, p. 11693 - 11702 (1995)
The total syntheses of wuweizisu C (4), gomisin J (6), gomisin N (7), and γ-schizandrin (8) having natural configuration were accomplished in a stereoselective manner.The catalytic hydrogenation or the metal mediated 1,4-reduction of the tetracyclic lactones (12, 17, 22, 30) played the significant role for the stereoselective introduction of C6, C7 dimethyl moiety.Furthermore, the neighboring carbonyl group assisted regioselective demethylation of 5 was essential for the synthesis of 6.
