66298-58-6

Basic information

• Product Name: Benzeneacetic acid, 2-(methoxycarbonyl)-, ethyl ester
• CAS NO: 66298-58-6
• Molecular Formula: C12H14O4
• Molecular Weight: 222.241
• Mol File: 66298-58-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, 2-(methoxycarbonyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, 2-(methoxycarbonyl)-, ethyl ester(66298-58-6)
• EPA Substance Registry System: Benzeneacetic acid, 2-(methoxycarbonyl)-, ethyl ester(66298-58-6)

Safety Data

• Hazardous Substances Data: 66298-58-6(Hazardous Substances Data)

Upstream product

• 22479-46-5 2-(ethoxycarbonylmethyl)benzoic acid 
• 75-03-6 ethyl iodide 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 5764-82-9 bromo(2-ethoxy-2-oxoethyl)zinc 
• 18267-36-2 ethyl 3-hydroxy-3-methylbutanoate 
• 89-51-0 Homophthalic acid 
• 4090-69-1 3-methoxy-1H-isochromen-1-one 
• 64-17-5 ethanol 

Downstream Products

• 118652-91-8 ethyl (E)-3-methoxy-2-(2'-methoxycarbonylphenyl)propenoate 

Relevant articles and documents

Photoinduced Palladium-Catalyzed Negishi Cross-Couplings Enabled by the Visible-Light Absorption of Palladium–Zinc Complexes

A visible-light-induced Negishi cross-coupling is enabled by the activation of a Pd0–Zn complex. With this photocatalytic method, the scope of deactivated aryl halides that can be employed in the Negishi coupling was significantly expanded. NMR experiments conducted in the presence and absence of light confirmed that the formation of the palladium–zinc complex is key for accelerating the oxidative addition step.

THE REGIO- AND STEREOCHEMISTRY OF THE ALKOXIDE-INDUCED RING-OPENING OF METHOXYMETHYLIDENE-SUBSTITUTED HOMOPHTHALIC ANHYDRIDE

Ring-opening of methoxymethylidene-substituted homophthalic anhydride (1) by methoxide occurs by two modes.Attack at the 1-position ("benzoate" carbonyl) leads to a stable acid-ester.A combination of unambiguous syntheses and 1H- and 13C-n.m.r. spectrosco