663-39-8 Usage
Description
(3beta,5alpha,6beta)-6-hydroxy-3,5-cycloandrostan-17-one is a steroidal compound belonging to the androstane class. It is a naturally occurring metabolite in the human body and plays a role in various biological processes. As a derivative of androstan-17-one, a key steroid hormone in the development and maintenance of male characteristics, the hydroxyl group at the 6th position of the molecule enhances its biological activity and interactions with other molecules in the body. (3beta,5alpha,6beta)-6-hydroxy-3,5-cycloandrostan-17-one may have potential pharmacological and therapeutic applications due to its involvement in hormone regulation and effects on the human body.
Uses
Used in Pharmaceutical Industry:
(3beta,5alpha,6beta)-6-hydroxy-3,5-cycloandrostan-17-one is used as a pharmaceutical agent for its potential involvement in hormone regulation and therapeutic effects on the human body. Its role in biological processes and interactions with other molecules make it a promising candidate for the development of new drugs and treatments.
Used in Hormone Regulation Research:
In the field of endocrinology, (3beta,5alpha,6beta)-6-hydroxy-3,5-cycloandrostan-17-one is used as a research compound to study hormone regulation and its effects on the body. Understanding its role in biological processes can contribute to the advancement of knowledge in endocrinology and the development of targeted therapies for hormone-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 663-39-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,6 and 3 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 663-39:
(5*6)+(4*6)+(3*3)+(2*3)+(1*9)=78
78 % 10 = 8
So 663-39-8 is a valid CAS Registry Number.
663-39-8Relevant articles and documents
Metabolic fate of 3α,5-cycloandrostanes in the endogenous lactonization pathway of Aspergillus tamarii KITA
Hunter, A. Christy,Patel, Shreyal,Dedi, Cinzia,Dodd, Howard T.,Bryce, Richard A.
, p. 19 - 25 (2015)
A series of 3α,5-cycloandrostane analogues with a range of functionality (6α and 6β alcohols and ketone) at carbon 6 were tested in the endogenous lactonization pathway in Aspergillus tamarii KITA. This metabolic route converts progesterone to testololactone in high yield through a four step enzymatic pathway. To date, no studies have looked at the effect of steroids devoid of polar functionality at carbon 3 and their subsequent metabolic fate by fungi which contain Baeyer-Villiger monooxygenases. Incubation of all of the cycloandrostane analogues resulted in lactonization of ring-D irrespective of C-6 stereochemistry or absence of C-3 functionality. Presence of 6β-hydroxy group and the C-17 ketone was required in order for these analogues to undergo hydroxylation at C-15β position. All metabolites were isolated by column chromatography and were identified by 1H, 13C NMR, DEPT analysis and other spectroscopic data.
The Participation of 3,5-Cyclosteroids in Aromatization Reactions
Hanson, James R.,Knights, Steve G.
, p. 1306 - 1310 (2007/10/02)
The preparation of 6β,7β-dihydroxy-3α-5-cycloandrostan-17-one and 2β,17β-diacetoxy-6α-hydroxy-3α,5-cycloandrostane and their reaction with hydrobromic acid in acetic acid is described.They both afford the corresponding 4-methylestratriene accompanied by,
