6633-40-5 Usage
Description
2-HYDROXY-7-NITROFLUORENE, also known as a major metabolite of 2-nitrofluorene (NF), is a yellow solid with significant estrogenic activity. It is a chemical compound that has been identified for its potential applications in various fields due to its unique properties.
Uses
Used in Pharmaceutical Industry:
2-HYDROXY-7-NITROFLUORENE is used as a pharmaceutical compound for its significant estrogenic activity. This characteristic makes it a potential candidate for the development of drugs targeting estrogen-related conditions and therapies.
Used in Research and Development:
In the field of research and development, 2-HYDROXY-7-NITROFLUORENE serves as an important chemical intermediate for the synthesis of various compounds with potential applications in medicine and other industries. Its unique chemical properties allow scientists to explore its potential in creating new drugs and materials.
Used in Environmental Monitoring:
As a metabolite of 2-nitrofluorene, 2-HYDROXY-7-NITROFLUORENE can be used in environmental monitoring to detect the presence of pollutants and assess the impact of industrial activities on the environment. This application helps in understanding the extent of pollution and taking necessary measures to mitigate its effects.
Used in Analytical Chemistry:
The chemical properties of 2-HYDROXY-7-NITROFLUORENE make it a useful compound in analytical chemistry for various purposes, such as the development of new analytical methods, the detection of specific substances, and the study of chemical reactions and interactions.
Fire Hazard
Flash point data for 2-HYDROXY-7-NITROFLUORENE are not available. 2-HYDROXY-7-NITROFLUORENE is probably combustible.
Check Digit Verification of cas no
The CAS Registry Mumber 6633-40-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,3 and 3 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6633-40:
(6*6)+(5*6)+(4*3)+(3*3)+(2*4)+(1*0)=95
95 % 10 = 5
So 6633-40-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H9NO3/c15-11-2-4-13-9(7-11)5-8-6-10(14(16)17)1-3-12(8)13/h1-4,6-7,15H,5H2
6633-40-5Relevant articles and documents
Cross-conjugation vs. linear conjugation in donor-bridge-acceptor nitrophenol chromophores
Christensen, Mikkel Andreas,Della Pia, Eduardo Antonio,Houmoller, Jorgen,Thomsen, Sean,Wanko, Marius,Bond, Andrew D.,Rubio, Angel,Brondsted Nielsen, Steen,Brondsted Nielsen, Mogens
, p. 2044 - 2052 (2014/04/17)
The influence of cross-conjugation vs. linear conjugation on the electronic communication between donor and acceptor groups in phenol(ate)-bridge- nitrobenzene chromophores was investigated by solution and gas-phase absorption spectroscopy, fluorescence s
Preneoplastic lesions, DNA adduct formation and mutagenicity of 5-, 7- and 9 -hydroxy-2-nitrofluorene, metabolites of the air pollutant 2-nitrofluorene
Cui, Xian-Shu,Bergman, Jan,Moeller, Lennart
, p. 147 - 155 (2007/10/03)
The metabolites of 2-nitrofluorene (NF), 5-, 7- and 9-OH-2-nitrofluorene (OH-NF) were compared for their genotoxicity. Seventy-two hours after intraperitoneal administration of these substances individually to rats (100 mg/kg body wt.), DNA adducts in liver tissue were analyzed with 32P-TLC and 32P-HPLC. An in vivo liver model was used to test the initiating capacity of the said substances for the formation of preneoplastic lesions. 5-OH-NF showed low capacity to induce DNA adduct formation and low potential as initiator to induce preneoplastic lesions-foci/nodules in the liver of rats. Both 7- and 9-OH-NF induced DNA adducts and preneoplastic liver lesions but with smaller quantities compared to NF. It seems that 7- and 9-OH-NF can not be considered as detoxification products of NF. In general, the initiating capacity of these substances for the formation of preneoplastic lesions has a good correlation with their potency to form DNA adducts.
