66348-92-3

Basic information

• Product Name: p-toluidinium p-toluidine-phenylmethanesulfonate
• CAS NO: 66348-92-3
• Molecular Weight: 384.499
• Mol File: 66348-92-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: p-toluidinium p-toluidine-phenylmethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: p-toluidinium p-toluidine-phenylmethanesulfonate(66348-92-3)
• EPA Substance Registry System: p-toluidinium p-toluidine-phenylmethanesulfonate(66348-92-3)

Safety Data

• Hazardous Substances Data: 66348-92-3(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 106-49-0 p-toluidine 
• 15795-42-3 N-sulfinyl-4-methylaniline 
• 540-23-8 p-toluidine hydrochloride 
• 4657-12-9 sodium hydroxy(phenyl)methanesulfonate 

Relevant articles and documents

MECHANISM OF AMINOMETHANESULFONATE FORMATION AND HYDROLYSIS REACTIONS

Based on kinetic, structural and synthetic evidence, a mechanism is proposed fro the synthesis of aminomethanesulfonates (R*NH*CHR'*SO3(1-)).The mechanism involves the initial protonation of the amine, proton transfer to the hydroxymethanesulfonate via a six-membered cyclic intermediate followed by a nucleophilic attack of the free amine on the carbon atom.The transition state is assumed to correspond to a structure with practically all the positive charge on the nitrogen atom.For the hydrolysis reaction, the initial protonation of the aminomethanesulfonate is followed by the nucleophilic attack of a water molecule.This mechanism is in agreement with the experimentally determined Hammett reaction constants ρ, i.e. -3.5 for the formation reaction and -2.3 for the hydrolysis.