6641-61-8

Basic information

• Product Name: 4-(4-nitrophenoxy)biphenyl
• Synonyms: 1,1'-Biphenyl, 4-(4-nitrophenoxy)-; 4-(4-Nitro-phenoxy)-biphenyl; benzene, 1-([1,1'-biphenyl]-4-yloxy)-4-nitro-; Biphenyl-4-yl 4-nitrophenyl ether
• CAS NO: 6641-61-8
• Molecular Formula: C₁₈H₁₃NO₃
• Molecular Weight: 291.3007
• Mol File: 6641-61-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 432.6°C at 760 mmHg
• Flash Point: 179.3°C
• Density: 1.228g/cm³
• Vapor Pressure: 2.76E-07mmHg at 25°C
• Refractive Index: 1.624
• CAS DataBase Reference: 4-(4-nitrophenoxy)biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-nitrophenoxy)biphenyl(6641-61-8)
• EPA Substance Registry System: 4-(4-nitrophenoxy)biphenyl(6641-61-8)

Safety Data

• Hazardous Substances Data: 6641-61-8(Hazardous Substances Data)

Upstream product

• 92-69-3 4-Phenylphenol 
• 100-00-5 4-chlorobenzonitrile 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 6628-69-9 4-([1,1'-biphenyl]-4-yloxy)aniline 

Relevant articles and documents

INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS

The present invention relates to new inhibitors of Notch signalling pathway and its use in the treatment and/or prevention of cancers.

A focused library of protein tyrosine phosphatase inhibitors

Protein tyrosine phosphatases such as PTP1B and YopH are potential targets for the development of therapeutic agents against a variety of pathological conditions including diabetes, obesity, and infection by the bacterium Yersinia pestis. A focused library of bidentate α-ketoacid-based inhibitors has been screened against several tyrosine phosphatases. Compound 2a has IC 50 values of 43 and 220 nM against YopH and PTP1B, respectively, and shows a 30-fold selectivity for PTP1B over the closely related phosphatase TCPTP.