66413-45-4Relevant articles and documents
Synthesis, structure - Activity relationships, and pharmacokinetic profiles of nonpeptidic α-keto heterocycles as novel inhibitors of human chymase
Akahoshi,Ashimori,Sakashita,Yoshimura,Eda,Imada,Nakajima,Mitsutomi,Kuwahara,Ohtsuka,Fukaya,Miyazaki,Nakamura
, p. 1286 - 1296 (2007/10/03)
We designed nonpeptidic chymase inhibitors based on the structure of a peptidic compound (1) and demonstrated that the combination of a pyrimidinone skeleton as a P3-P2 scaffold and heterocycles as P1 carbonyl-activating g
Process for producing optically active cyanohydrins
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, (2008/06/13)
An optically active cyanohydrin represented by the following general formula (1): STR1 wherein each of R1 and R2 is a hydrogen atom or an amino-protecting group, and the configurations relating to the carbon atoms at the *2-position and *3-position are as