6642-39-3

Basic information

• Product Name: 1-(2-methoxyphenyl)-2-methyl-propan-1-ol
• Synonyms: 1-(2-methoxyphenyl)-2-methyl-propan-1-ol
• CAS NO: 6642-39-3
• Molecular Formula: C₁₁H₁₆O₂
• Molecular Weight: 180.24
• Mol File: 6642-39-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 284.1°C at 760 mmHg
• Flash Point: 116.4°C
• Appearance: /
• Density: 1.013g/cm³
• Vapor Pressure: 0.00143mmHg at 25°C
• Refractive Index: 1.51
• PKA: 14.36±0.20(Predicted)
• CAS DataBase Reference: 1-(2-methoxyphenyl)-2-methyl-propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-methoxyphenyl)-2-methyl-propan-1-ol(6642-39-3)
• EPA Substance Registry System: 1-(2-methoxyphenyl)-2-methyl-propan-1-ol(6642-39-3)

Safety Data

• Hazardous Substances Data: 6642-39-3(Hazardous Substances Data)

Usage

Physical state

Colorless to pale yellow liquid

Odor

Strong, sweet, and spicy

Natural occurrence

Found in essential oils such as clove oil, nutmeg, and cinnamon

Uses in the food and beverage industry

Flavoring agent

Uses in perfumes and cosmetics

Fragrance

Traditional medicinal uses

Analgesic, antiseptic, and anti-inflammatory properties

Application in dentistry

Numbing effect in dental procedures

Pharmacological properties

Potential applications in the pharmaceutical industry

InChI:InChI=1/C11H16O2/c1-8(2)11(12)9-6-4-5-7-10(9)13-3/h4-8,11-12H,1-3H3

Upstream product

• 74786-53-1 1-(2-methoxyphenyl)-2-methylpropan-1-one 
• 920-39-8 isopropylmagnesium bromide 
• 111289-42-0 bis(2-methoxybenzoyl) telluride 
• 2040-20-2 4-methoxyisobutyrophenone 
• 16750-63-3 2-methoxyphenylmagnesium bromide 
• 78-84-2 isobutyraldehyde 
• 135-02-4 ortho-anisaldehyde 
• 75-30-9 2-iodo-propane 

Downstream Products

• 499236-03-2 1-(1-Chloro-2-methylpropyl)-2-methoxybenzene 
• 91967-51-0 1-isobutyl-2-methoxybenzene 
• 4167-75-3 2-isobutylphenol 
• 6026-72-8 1-(2-methoxyphenyl)-2-methylprop-1-ene 

Relevant articles and documents

Bimetallic Catalysis: Asymmetric Transfer Hydrogenation of Sterically Hindered Ketones Catalyzed by Ruthenium and Potassium

An efficient protocol for the asymmetric reduction of sterically hindered ketones under transfer-hydrogenation conditions was developed. The corresponding chiral alcohols were obtained in good to excellent yields with enantiomeric excess values up to 99 %. The role of the cation associated with the base present in the reduction reaction was investigated. In contrast to previous studies on this catalyst system, potassium ions rather than lithium ions significantly enhanced the reaction outcome.

Reaction of secondary and tertiary aliphatic halides with aromatic aldehydes mediated by chromium(II): a selective cross-coupling of alkyl and ketyl radicals

Takai-Utimoto reactions with secondary and tertiary aliphatic halides usually failed according to previous reports. Now, significant improvements could be achieved, and especially secondary aliphatic halides can be coupled to aromatic aldehydes in yields of up to >95%. A variety of processes are competing with the desired one, and thus conditions must be adapted to the nature of the aldehyde as well as the aliphatic halide used, as the outcome of these reactions is strongly affected by the putative radical intermediates.

Hypercoordinafion of boron and aluminum: Synthetic utility as chelating lewis acids [7]

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