664351-09-1

Basic information

• Product Name: 1-BENZYL-5-METHYL-1H-1,2,3-TRIAZOLE-4-CARBONYL CHLORIDE
• Synonyms: 1-BENZYL-5-METHYL-1H-1,2,3-TRIAZOLE-4-CARBONYL CHLORIDE;1-Benzyl-4-(chloroformyl)-5-methyl-1H-1,2,3-triazole, 5-Methyl-1-(phenylmethyl)-1H-1,2,3-triazole-4-carbonyl chloride;1-Benzyl-5-methyl-1H-1,2,3-triazole-4-carbonylchloride97%
• CAS NO: 664351-09-1
• Molecular Formula: C₁₁H₁₀ClN₃O
• Molecular Weight: 235.67
• Product Categories: Carbonyl Chlorides;Pyrazoles & Triazoles;Carbonyl Chlorides;Pyrazoles & Triazoles
• Mol File: 664351-09-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 94-95°
• Appearance: /
• CAS DataBase Reference: 1-BENZYL-5-METHYL-1H-1,2,3-TRIAZOLE-4-CARBONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZYL-5-METHYL-1H-1,2,3-TRIAZOLE-4-CARBONYL CHLORIDE(664351-09-1)
• EPA Substance Registry System: 1-BENZYL-5-METHYL-1H-1,2,3-TRIAZOLE-4-CARBONYL CHLORIDE(664351-09-1)

Safety Data

• Hazard Codes: C
• HazardClass: IRRITANT
• Hazardous Substances Data: 664351-09-1(Hazardous Substances Data)

Usage

Type of compound

Carboxylic acid chloride derivative

Appearance

White to off-white solid

Synthesis origin

1-benzyl-5-methyl-1H-1,2,3-triazole-4-carboxylic acid

Usage

Synthetic intermediate in organic chemistry

Applications

Synthesis of pharmaceuticals and agrochemicals

Importance

Building block for triazole-containing compounds with diverse applications in medicine and agriculture

Reactivity

Reactive with water and other reactive chemicals, requiring careful handling and storage

Safety precautions

Exercise caution to prevent violent reactions with water and other chemicals

Upstream product

• 100-39-0 benzyl bromide 
• 622-79-7 benzyl azide 
• 133992-58-2 1-benzyl-5-methyl-1H-1,2,3-triazol-4-carboxylic acid ethyl ester 
• 54698-60-1 1-benzyl-5-methyl-1H-1,2,3-triazole-4-carboxylic acid 

Relevant articles and documents

Tri-Substituted Triazole-Enabled C-H Activation of Benzyl and Aryl Amines by Iron Catalysis

The design of trisubstituted triazoles set the stage for proximity-induced iron-catalyzed C-H activation of benzyl and aryl amines with ample scope. Thereby, C-H alkylations and C-H arylations proved viable with high levels of chemo and positional selectivities by means of racemization-free iron catalysis with the reusable triazole being removed in a traceless fashion.

SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF

Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.

N6-cycloalkyl-2-phenyl-3-deaza-8-azaadenines: a new class of A1 adenosine receptor ligands. A comparison with the corresponding adenines and 8-azaadenines.

Several 9-benzyl-N6-cycloalkyl-2-phenyladenines, 9-benzyl-N6-cycloalkyl-2-phenyl-8-azaadenines and 4-cycloalkylamino-1-benzyl-6-phenyl-1H-1,2,3-triazolo[4,5-c]pyridines were prepared and assayed as A1 adenosine receptor ligands. The 1H-1,2,3-triazolo[4,5-