66448-21-3

Basic information

• Product Name: Acetic acid, (hydroxymethoxyphosphinyl)-
• CAS NO: 66448-21-3
• Molecular Formula: C3H7O5P
• Molecular Weight: 154.059
• Mol File: 66448-21-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid, (hydroxymethoxyphosphinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, (hydroxymethoxyphosphinyl)-(66448-21-3)
• EPA Substance Registry System: Acetic acid, (hydroxymethoxyphosphinyl)-(66448-21-3)

Safety Data

• Hazardous Substances Data: 66448-21-3(Hazardous Substances Data)

Upstream product

• 5927-18-4 trimethyl phosphonoacetate 

Relevant articles and documents

Composition on the basis of phosphonoacetic acid. Synthesis and antiviral activity

A manufacturable technology for the production of an antiviral composition containing phosphonoacetic acid, involing PH-alkylation of dimethyl phosphite with methyl chloroacetate under phase-transfer conditions and subsequent in situ hydrolysis of the intermediate product, was developed. The composition showed expressed antiviral effect against herpesviral infections caused by herpes simplex virus 1 and 2 and cytomegalovirus. The composition in the effective concentration range was found to exhibit no cytotoxic effect on VERO green monkey kidney and M-19 human diploid cell cultures. The resulting data suggest potential uses of the composition as an antiviral agent in practical medicine and as an antiviral additive to synthetic detergents for sanitation in health care and food production facilities.