6645-65-4

Basic information

• Product Name: 1,4-Benzenedicarboxylic acid, bis(2-phenylhydrazide)
• CAS NO: 6645-65-4
• Molecular Formula: C20H18N4O2
• Molecular Weight: 346.389
• Mol File: 6645-65-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,4-Benzenedicarboxylic acid, bis(2-phenylhydrazide)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Benzenedicarboxylic acid, bis(2-phenylhydrazide)(6645-65-4)
• EPA Substance Registry System: 1,4-Benzenedicarboxylic acid, bis(2-phenylhydrazide)(6645-65-4)

Safety Data

• Hazardous Substances Data: 6645-65-4(Hazardous Substances Data)

Usage

Physical state

White solid

Usage

Intermediate for the synthesis of various organic compounds

Applications

Production of dyes, pharmaceuticals, and polymers

Role

Reactive agent in the formation of complex organic molecules

Potential use

Anti-cancer drugs and other medicinal applications

Field of relevance

Organic chemistry

Upstream product

• 100-63-0 phenylhydrazine 
• 100-20-9 terephthaloyl chloride 

Relevant articles and documents

Use of acylhydrazine- and acylhydrazone-type ligands to promote CuI-catalyzed C-N cross-coupling reactions of aryl bromides with N-heterocycles

A series of ten acylhydrazine- and acylhydrazone-type ligands were designed and synthesized. Their electronic and steric properties were easily modified and tuned by varying the substituents in the vicinity of the acylhydrazine and acylhydrazone units. The effect of ligands on the catalytic activity of Ullmann reactions was assessed by using a combination of these ligands with CuI. The catalytic system is very efficient for the C-N coupling reaction of azoles with aryl and heteroaryl bromides. A simple and efficient procedure for copper-catalyzed C-N cross-coupling reactions between aryl bromides and NH-containingheterocycles is illustrated. Readily available acylhydrazine- and acylhydrazone-typeligands promote the reaction.