6647-96-7Relevant articles and documents
2 - Alkynyl mannose derivative and application thereof
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Paragraph 0082-0084, (2021/10/05)
The present invention relates to a 2-alkynyl mannose derivative and an application thereof. The mannose derivative, as well as a pharmaceutically acceptable salt, an isotope and an isomer thereof have the structure represented by general formula I. The de
Two-stage sonogashira coupling method in the synthesis of auxin active acetylenes
Wayne Craig,Eberle, Martin,Irminger, Bruno,Schueckenboehmer, Anegret,Laime, Yvette,Mueller, Patrick
, p. 1967 - 1974 (2008/09/16)
A sequential Sonogashira coupling of a protected acetylene precursor with aryl halides (5) followed by pyrazolyl iodides (14) allows efficient access to the unsymmetrical aryl-heteroarylacetylene (8). Subsequent regioselective lithiation exchange followed by dimethyl oxalate quench produced readily vicinal ketoesters (9) which show auxin effects in a wide variety of plant species.