66511-82-8

Basic information

• Product Name: (1S,2S,4R)-2-amino-1-methyl-4-(1-methylethenyl)cyclohexanol
• Synonyms: (1S,2S,4R)-2-amino-1-methyl-4-(1-methylethenyl)cyclohexanol
• CAS NO: 66511-82-8
• Molecular Weight: 169.267
• Mol File: 66511-82-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1S,2S,4R)-2-amino-1-methyl-4-(1-methylethenyl)cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S,4R)-2-amino-1-methyl-4-(1-methylethenyl)cyclohexanol(66511-82-8)
• EPA Substance Registry System: (1S,2S,4R)-2-amino-1-methyl-4-(1-methylethenyl)cyclohexanol(66511-82-8)

Safety Data

• Hazardous Substances Data: 66511-82-8(Hazardous Substances Data)

Upstream product

• 1195-92-2 (4R)-limonene 1,2-epoxide 
• 5989-27-5 D-limonene 
• 200437-33-8 (1S,2S,5R)-2-azido-2-methyl-5?(prop-1-en-2-yl)cyclohexanol 
• 6909-30-4 (1S,2R,4R)-limonene-1,2-epoxide 

Downstream Products

• 72552-28-4 (1S,2S,5R)-5-Isopropenyl-2-methoxy-2-methyl-cyclohexylamine 

Relevant articles and documents

Chiral amino and imino-alcohols based on (R)-limonene

Derivatives of the natural occurring and inexpensive terpene (R)-limonene were synthetized and completely characterized. Starting from internal olefin epoxidation, followed by epoxide opening with sodium azide and azide reduction with LiAlH4, two chiral amino-alcohols were obtained. The amino-alcohols were reacted with three different aldehydes, generating six new imino-alcohols, two of them yielding crystals suitable for X-ray diffraction characterization. The reduction of four of these compounds with LiAlH4 led to new amino-alcohols. All derivatives were obtained with good overall yields through simple reaction protocols.