6652-16-0

Basic information

• Product Name: 4-(3-TRIFLUOROMETHYLPHENYL)PIPERIDINE HYDROCHLORIDE
• Synonyms: 4-(3-TRIFLUOROMETHYLPHENYL)PIPERIDINE HYDROCHLORIC SALT;4-(3-TRIFLUOROMETHYLPHENYL)PIPERIDINE HYDROCHLORIDE;3-Trifluoromethylphenylpiperidine hydrochloride;4[3-(TRIFLUOROMETHYL)PHENYL] PIPERIDINE HCL;4-[3'-(TRIFLUOROMETHYL)PHENYL]PIPERIDINE HCL
• CAS NO: 6652-16-0
• Molecular Formula: C₁₂H₁₄F₃N*ClH
• Molecular Weight: 265.7
• Product Categories: Piperidine;Miscellaneous
• Mol File: 6652-16-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 206-208 °C
• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 4-(3-TRIFLUOROMETHYLPHENYL)PIPERIDINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-TRIFLUOROMETHYLPHENYL)PIPERIDINE HYDROCHLORIDE(6652-16-0)
• EPA Substance Registry System: 4-(3-TRIFLUOROMETHYLPHENYL)PIPERIDINE HYDROCHLORIDE(6652-16-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-36-52
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 6652-16-0(Hazardous Substances Data)

Usage

General Description

4-(3-Trifluoromethylphenyl)piperidine hydrochloride is a chemical compound with the molecular formula C12H16F3N. It is a piperidine derivative with a trifluoromethylphenyl group attached to the piperidine ring. 4-(3-TRIFLUOROMETHYLPHENYL)PIPERIDINE HYDROCHLORIDE is typically used as a reagent in organic synthesis and pharmaceutical research. It may also have potential applications in the development of new medications due to its interactions with biological systems. Additionally, the hydrochloride salt form of this compound increases its solubility in water, making it easier to handle and use in various laboratory settings. Overall, 4-(3-Trifluoromethylphenyl)piperidine hydrochloride is a versatile chemical that can be used in a variety of research and development applications.

InChI:InChI=1/C12H14F3N.ClH/c13-12(14,15)11-3-1-2-10(8-11)9-4-6-16-7-5-9;/h1-3,8-9,16H,4-7H2;1H

Upstream product

• 56108-27-1 1-benzyl-4-(3-trifluoromethylphenyl)piperidin-4-ol 
• 401-78-5 3-bromo-1-trifluoromethylbenzene 
• 84447-17-6 C₁₉H₁₈F₃N*ClH 
• 346688-68-4 1-benzyl-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 2249-28-7 4-(3-trifluoromethylphenyl)-4-hydroxy piperidine 
• 250289-99-7 7-(2,3-epoxypropoxy)-2,3-dihydro-2,2-dimethylbenzofuran 

Downstream Products

• 1683-49-4 4-hydroxy-4-(3-trifluoromethylphenyl)piperidine hydrochloride 
• 1229418-79-4 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid [4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-5'-yl]-amide 
• 1229419-19-5 4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-5'-ylamine 
• 1229419-20-8 5'-nitro-4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl 
• 1224869-59-3 4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-5'-carboxylic acid (5-methyl-4-phenyl-thiazol-2-yl)-amide 

Relevant articles and documents

Synthesis and SAR study of 4-arylpiperidines and 4-aryl-1,2,3,6- tetrahydropyridines as 5-HT2C agonists

A series of substituted 4-arylpiperidines and a smaller family of 4-aryl-1,2,3,6-tetrahydropyridines were synthesized and their biological activity at the 5-HT2C receptor studied to determine whether either series showed noteworthy agonist activity. Structure-activity relationships were developed from the performed receptor binding assays and functional studies, and the results of the analysis are presented herein.

Modulators of dopamine neurotransmission

A 3-substituted 4-(phenyl-N-alkyl)-piperazine compound of the following formula: wherein R1 is selected from the group consisting of OSO2CF3, OSO2CH3, SO2R3, COCF3, CO