66640-93-5

Basic information

• Product Name: DFMO
• Synonyms: ALPHA-DIFLUORO-ME-DL-ORNITHINE;ALPHA-DIFLUOROMETHYL-DL-ORNITHINE;DFMO;EFLORNITINE;DL-ALPHA-DIFLUOROMETHYLORNITHINE;DIFLUOROMETHYLORNITHINE;H-DL-(F2ME)ORN-OH;H-DL-(ALPHA-DIFLUOROMETHYL)ORN-OH
• CAS NO: 66640-93-5
• Molecular Formula: C6H12F2N2O2
• Molecular Weight: 182.17
• Mol File: 66640-93-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 347.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.293±0.06 g/cm3(Predicted)
• PKA: 1.22±0.44(Predicted)
• CAS DataBase Reference: DFMO(CAS DataBase Reference)
• NIST Chemistry Reference: DFMO(66640-93-5)
• EPA Substance Registry System: DFMO(66640-93-5)

Safety Data

• Hazardous Substances Data: 66640-93-5(Hazardous Substances Data)

Upstream product

• 501011-48-9 ethyl 2-(diphenylmethylene)amino-2-difluoromethyl-4-cyanobutanoate 
• 501011-46-7 ethyl 2-amino-2-difluoromethyl-4-cyanobutanoate 

Downstream Products

• 69955-43-7 DL-α-difluoromethylarginine 

Relevant articles and documents

Catalytic hydrogenation of ethyl 2-amino-2-difluoromethyl-4-cyanobutanoate and its Schiff base reaction modes

Under heterogeneous catalysis, ethyl 2-amino-2-difluoromethyl-4- cyanobutanoate or its Schiff base could be selectively reduced in good yield by hydrogenation to give a diamine, or to form a five-membered ring or a six-membered ring heterocycles. This selectivity is highly dependent on the type of catalysts used.

Method of inhibiting the growth of protozoa

α-Substituted amines and α-substituted-α-amino acids are described which are useful in inhibiting the growth of protozoa in animals.