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66642-35-1

66642-35-1

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  • 2-Pyrrolidinecarboxamide,N-(4-nitrophenyl)-5-oxo-, (2S)-

    Cas No: 66642-35-1

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66642-35-1 Usage

Chemical Properties

Light yellow crystalline powder

Uses

Substrate for pyrrolidonylpeptidase.

Check Digit Verification of cas no

The CAS Registry Mumber 66642-35-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,6,4 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 66642-35:
(7*6)+(6*6)+(5*6)+(4*4)+(3*2)+(2*3)+(1*5)=141
141 % 10 = 1
So 66642-35-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H11N3O4/c15-10-6-5-9(13-10)11(16)12-7-1-3-8(4-2-7)14(17)18/h1-4,9H,5-6H2,(H,12,16)(H,13,15)/t9-/m0/s1

66642-35-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name PYR-PNA

1.2 Other means of identification

Product number -
Other names L-PYROGLUTAMIC ACID 4-NITROANILIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:66642-35-1 SDS

66642-35-1Downstream Products

66642-35-1Relevant articles and documents

Synthesis and bioactivities evaluation of L-pyroglutamic acid analogues from natural product lead

Gang, Fang-li,Zhu, Feng,Li, Xiao-ting,Wei, Jie-lu,Wu, Wen-jun,Zhang, Ji-wen

, p. 4644 - 4649 (2018/08/21)

A series of L-pyroglutamic acid analogues from natural product lead were designed and synthesized, as well as their antifungal activities against Phytophthora infestans, neuritogenic activities, antibacterial activities and anti-inflammatory activities are described. The bioassays and SAR study showed that the majority of L-pyroglutamic acid esters have a significant antifungal activity against P. infestans, especially 2d and 2j demonstrated the best activities with EC50 values of 1.44 and 1.21 μg mL?1, which were about seven times that of commercial azoxystrobin (7.85 μg mL?1). Moreover, compounds 2e, 2g and 4d displayed anti-inflammatory activity against LPS-induced NO production in BV-2 microglial cells; neuritogenic activity in NGF-induced PC-12 cells is the same activity. This study demonstrates that compounds 2d and 2j are potential drugs to control P. infestans.

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