66778-24-3

Basic information

• Product Name: Naphthalene, 2-(2-methylphenyl)-
• CAS NO: 66778-24-3
• Molecular Formula: C17H14
• Molecular Weight: 218.298
• Mol File: 66778-24-3.mol
• Article Data: 47

Chemical Properties

• CAS DataBase Reference: Naphthalene, 2-(2-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Naphthalene, 2-(2-methylphenyl)-(66778-24-3)
• EPA Substance Registry System: Naphthalene, 2-(2-methylphenyl)-(66778-24-3)

Safety Data

• Hazardous Substances Data: 66778-24-3(Hazardous Substances Data)

Upstream product

• 580-13-2 2-bromonaphthalene 
• 583-60-8 2-Methylcyclohexanone 
• 16419-60-6 2-Methylphenylboronic acid 
• 201230-82-2 carbon monoxide 
• 450-58-8 2-naphthyldiazonium tetrafluoroborate 
• 932-31-0 ortho-tolylmagnesium bromide 
• 91-20-3 naphthalene 
• 82166-21-0 methyl cyclohexane 
• 7385-85-5 naphthalen-2-yl tosylate 
• 1523-11-1 naphthalen-2-yl acetate 
• 7294-50-0 tri-o-tolylboroxine 
• 10290-91-2 naphthalen-2-yl methanesulfonate 
• 158715-24-3 trimethoxy(2-methylphenyl)silane 
• 95-46-5 2-methylphenyl bromide 

Relevant articles and documents

Arylketones as Aryl Donors in Palladium-Catalyzed Suzuki-Miyaura Couplings

Herein, we report the arylation, alkylation, and alkenylation of aryl ketones via a palladium-catalyzed Suzuki-Miyaura cross-coupling reaction. The use of the pyridine-oxazoline ligand is the key to the cleavage of the unstrained C-C bond. The late-stage arylation of aryl ketones derived from drugs and natural products demonstrated the synthetic utility of this protocol.

METHOD FOR SYNTHESIZING BORONATE ESTER COMPOUND, SODIUM SALT OF BORONATE ESTER COMPOUND, AND METHOD FOR SYNTHESIZING THE SAME

An object is to establish a technology with which a boronate ester compound can be easily and efficiently synthesized at a low cost with a small number of steps without the need for a complex chemical method and reagents that need to be carefully handled. A further object is to establish a sodium salt of a boronate ester compound that is a novel compound and a technology for synthesizing the sodium salt of a boronate ester compound. Provided are a sodium salt of a boronate ester compound and a method for synthesizing a boronate ester compound or a sodium salt of a boronate ester compound that includes reacting, in a reaction solvent, an organic chloride with a dispersion product obtained by dispersing sodium in a dispersion solvent to obtain an organic sodium compound, and reacting the obtained organic sodium compound with a borate ester compound to obtain a boronate ester compound or a sodium salt of a boronate ester compound.

N,S-chelating triazole-thioether ligand for highly efficient palladium-catalyzed Suzuki reaction

1,2,3-Triazole-thioether compounds could serve as efficient ligands for Pd-catalyzed Suzuki reactions of various aryl iodides, bromides and chlorides. The reactions feature wide substrate scope and mild reaction conditions. Besides, shorter reaction time, lower catalyst loadings and quantitative yields with a turnover-frequency (TOF) value of up to 11,880 h?1 are other advantageous of this attractive protocol. The crystal structure analyses and computational studies revealed that the higher catalytic activity of the corresponding chelated palladium complex ascribed to the lower energy gap and the lower redox potential.