66783-83-3

Basic information

• Product Name: N-(9H-fluorene-9-ylidine)-4-methoxyaniline oxide
• Synonyms: N-(9H-fluorene-9-ylidine)-4-methoxyaniline oxide
• CAS NO: 66783-83-3
• Molecular Weight: 301.345
• Mol File: 66783-83-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(9H-fluorene-9-ylidine)-4-methoxyaniline oxide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(9H-fluorene-9-ylidine)-4-methoxyaniline oxide(66783-83-3)
• EPA Substance Registry System: N-(9H-fluorene-9-ylidine)-4-methoxyaniline oxide(66783-83-3)

Safety Data

• Hazardous Substances Data: 66783-83-3(Hazardous Substances Data)

Upstream product

• 5455-02-7 9-<(4-methoxyphenyl)imino>fluorene 
• 2157-52-0 9-fluorenone oxime 

Downstream Products

• 70765-98-9 4'-tert-butyl-3'-(4-methoxy-phenyl)-5'-oxo-spiro[fluorene-9,2'-oxazolidine]-4'-carbonitrile 

Relevant articles and documents

Cycloaddition of Fluorenone N-Aryl Nitrones with Methylenecyclopropanes and Sequential 1,3-Rearrangement: An Entry to Synthesis of Spirofluorenylpiperidin-4-ones

A facile synthesis of various spirofluorenylpiperidin-4-ones has been achieved in good yields from fluorenone N-aryl nitrones and methylenecyclopropanes. This method involved an initial cycloaddition to form a 5-spirocyclopropane-isoxazoline, which underwent a highly selective 1,3-rearrangement to give the desired product. The stereochemistry of the spirofluorenylpiperidin-4-one could be controlled by the cycloaddition and sequential rearrangement strategy. Furthermore, the spirofluorenylpiperidin-4-ones could be not only prepared in one-pot procedure but also converted to useful scaffolds by reduction or oxidation conditions.