66788-06-5

Basic information

• Product Name: (9R,10R)-9,10-dihydrobenzo[e]pyrene-9,10-diol
• CAS NO: 66788-06-5
• Molecular Formula: C₂₀H₁₄O₂
• Molecular Weight: 286.324
• Mol File: 66788-06-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 553.3°C at 760 mmHg
• Flash Point: 268.6°C
• Density: 1.46g/cm³
• Vapor Pressure: 4.47E-13mmHg at 25°C
• Refractive Index: 1.911
• CAS DataBase Reference: (9R,10R)-9,10-dihydrobenzo[e]pyrene-9,10-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (9R,10R)-9,10-dihydrobenzo[e]pyrene-9,10-diol(66788-06-5)
• EPA Substance Registry System: (9R,10R)-9,10-dihydrobenzo[e]pyrene-9,10-diol(66788-06-5)

Safety Data

• Hazardous Substances Data: 66788-06-5(Hazardous Substances Data)

Usage

Description

(9R,10R)-9,10-dihydrobenzo[e]pyrene-9,10-diol is a chemical compound belonging to the class of benzo[e]pyrene derivatives. It is a dihydroxy derivative of benzo[e]pyrene, a polycyclic aromatic hydrocarbon (PAH) that is an environmental pollutant found in tobacco smoke and vehicle emissions. (9R,10R)-9,10-dihydrobenzo[e]pyrene-9,10-diol features two hydroxyl groups at the 9 and 10 positions and is recognized as a potential carcinogen and mutagen. Its structure and properties are significant for understanding the toxicological effects of benzo[e]pyrene exposure and for developing strategies to mitigate its harmful effects on human health and the environment.

Uses

Used in Environmental Research:
(9R,10R)-9,10-dihydrobenzo[e]pyrene-9,10-diol is used as a research compound for studying the environmental impact of PAHs, particularly benzo[e]pyrene. Its role in understanding the toxicological effects and potential carcinogenic properties of benzo[e]pyrene exposure aids in the development of environmental protection strategies.
Used in Toxicology and Health Research:
In the field of toxicology and health research, (9R,10R)-9,10-dihydrobenzo[e]pyrene-9,10-diol serves as a model compound to investigate the mechanisms of carcinogenesis and mutagenicity associated with PAH exposure. This knowledge is crucial for the development of preventive measures and treatments against PAH-induced health issues.
Used in Analytical Chemistry:
(9R,10R)-9,10-dihydrobenzo[e]pyrene-9,10-diol is utilized as a reference material in analytical chemistry for the development and validation of methods to detect and quantify PAHs in environmental and biological samples. Accurate measurement of these compounds is essential for assessing exposure risks and implementing effective pollution control measures.
Used in Pharmaceutical Research:
Although (9R,10R)-9,10-dihydrobenzo[e]pyrene-9,10-diol itself is a potential carcinogen, its study may contribute to the development of pharmaceuticals that can counteract or mitigate the harmful effects of PAHs. Understanding its mechanism of action can lead to the design of drugs that target similar pathways, thus offering potential therapeutic benefits.

Upstream product

• 68151-07-5 4-(1,2,3,6,7,8-hexahydro-pyren-4-yl)-4-oxo-butyric acid 
• 68151-11-1 trans-9,10-dibenzoyloxy-1,2,3,6,7,8,9,10,11,12-decahydrobenzopyrene 
• 66787-95-9 Methyl-γ-1,2,3,6,7,8-hexahydro-4-pyrenylbutyrat 
• 66787-94-8 4-(1,2,3,6,7,8-hexahydro-pyren-4-yl)-butyric acid 
• 66787-96-0 Methyl-4-pyrenylbutyrat 
• 66787-97-1 9-oxo-9,10,11,12-tetrahydrobenzopyrene 
• 66788-00-9 9-Hydroxy-9,10,11,12-tetrahydrobenzopyrene 
• 66788-01-0 9,10-Dihydrobenzopyrene 
• 68151-10-0 1,2,3,6,7,8,9,10-Octahydrobenzopyrene 
• 82120-24-9 benzopyrene-9,10-dione 

Relevant articles and documents

Efficient Synthesis of Non-K-Region trans-Dihydro Diols of Polycyclic Aromatic Hydrocarbons from o-Quinones and Catechols

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