668419-17-8

Basic information

• Product Name: Benzenesulfonamide, N-[2-(1H-indol-3-yl)-1-methylethyl]-2,4,6-trimethyl-
• CAS NO: 668419-17-8
• Molecular Formula: C20H24N2O2S
• Molecular Weight: 356.489
• Mol File: 668419-17-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-[2-(1H-indol-3-yl)-1-methylethyl]-2,4,6-trimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-[2-(1H-indol-3-yl)-1-methylethyl]-2,4,6-trimethyl-(668419-17-8)
• EPA Substance Registry System: Benzenesulfonamide, N-[2-(1H-indol-3-yl)-1-methylethyl]-2,4,6-trimethyl-(668419-17-8)

Safety Data

• Hazardous Substances Data: 668419-17-8(Hazardous Substances Data)

Upstream product

• 773-64-8 2-mesitylenesulphonyl chloride 
• 299-26-3 1-(1H-indol-3-yl)propan-2-amine 

Downstream Products

• 668420-23-3 3-[2-(2,4,6-trimethylbenzenesulfonylamino)propyl]indole-1-carboxylic acid tert-butyl ester 
• 668420-24-4 3-{2-[methyl-(2,4,6-trimethylbenzenesulfonyl)amino]propyl}indole-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

α-Methyltryptamine sulfonamide derivatives as novel glucocorticoid receptor ligands

α-Methyltryptamine sulfonamides were identified as human glucocorticoid receptor (hGR) ligands in an ultra high throughput screening (UHTS) campaign. Described will be the hit-to-lead activities, including parallel and single point analog synthesis to map the scaffold. Ligands were identified that exhibited 30 nM binding to hGR. The SAR and selectivity of these compounds will be discussed.