66866-65-7

Basic information

• Product Name: 3-Oxazolidinecarboxylic acid, 4-[(1S)-1-methylpropyl]-5-oxo-, phenylmethyl ester, (4S)-
• CAS NO: 66866-65-7
• Molecular Formula: C15H19NO4
• Molecular Weight: 277.31600
• Mol File: 66866-65-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-Oxazolidinecarboxylic acid, 4-[(1S)-1-methylpropyl]-5-oxo-, phenylmethyl ester, (4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxazolidinecarboxylic acid, 4-[(1S)-1-methylpropyl]-5-oxo-, phenylmethyl ester, (4S)-(66866-65-7)
• EPA Substance Registry System: 3-Oxazolidinecarboxylic acid, 4-[(1S)-1-methylpropyl]-5-oxo-, phenylmethyl ester, (4S)-(66866-65-7)

Safety Data

• Hazardous Substances Data: 66866-65-7(Hazardous Substances Data)

Upstream product

• 73-32-5 L-isoleucine 
• 50-00-0 formaldehyd 
• 3160-59-6 N-Cbz-L-Isoleucine 
• 319-78-8 isoleucine 
• 61548-98-9 C₉H₉NO₂C₂H₃CHC 
• 3160-59-6 N-benzyloxycarbonyl-isoleucine 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 163887-30-7 N-Z-N-Me-(S,R)-Ile 
• 922705-52-0 (3R,4S)-4-methyl-3-(methyl{[(phenylmethyl)oxy]carbonyl}amino)hexanoic acid 
• 922705-71-3 phenylmethyl [(1S,2S)-1-(diazoacetyl)-2-methylbutyl]methylcarbamate 
• 42417-66-3 (2S,3S)-3-methyl-2-(methyl{[(phenylmethyl)oxy]carbonyl}amino)pentanoic acid 
• 6216-62-2 (2S,3S)-2-<(benzyloxycarbonyl)amino>-3-methylpentan-1-ol 
• 4125-95-5 (S)-Z-N-Methylisoleucine 

Relevant articles and documents

A novel synthesis of N-but-3-enyl-α- and β-amino acids

N-But-3-enyl-α- and β-amino acids can be prepared by cleaving 1,3-oxazolidin-5-ones and 1,3-oxazinan-6-ones in the presence of allylsilanes and boron trifluoride etherate at room temperature in good to excellent yields. Georg Thieme Verlag Stuttgart.

Determination of the complete absolute configuration of petriellin A

We report the full structural determination of the depsipeptide petriellin A. The absolute configuration of the amino acid residues, N-methyl isoleucine and N-methyl threonine, have been determined by a combination of HPLC and TLC comparison of synthetic Marfey's derivatives and Marfey's derivatives of the natural product hydrolysate. The configuration of the chiral centres in these two N-methylated residues was found to be the same as those of the common unmethylated l-amino acids. CSIRO 2006.

SYNTHESIS OF DERIVATIVES OF OXAZOLIDIN-5-ONES

A method has been developed for the synthesis of derivatives of oxazolidin-5-one by the reaction of the corresponding N-benzyloxycarbonylaminoacid with formaldehyde in the presence of formic acid.Yields of derivatives of 3-benzyloxycarbonyloxazolidin-5-on