669004-75-5Relevant articles and documents
New chemotypes for cathepsin K inhibitors
Teno, Naoki,Irie, Osamu,Miyake, Takahiro,Gohda, Keigo,Horiuchi, Miyuki,Tada, Sachiyo,Nonomura, Kazuhiko,Kometani, Motohiko,Iwasaki, Genji,Betschart, Claudia
, p. 2599 - 2603 (2008/12/21)
Cyano pyrimidine acetylene and cyano pyrimidine t-amine, which belong to a new chemical class, were prepared and tested for inhibitory activities against cathepsin K and the highly homologous cathepsins L and S. The use of novel chemotypes in the developm