66934-18-7 Usage
Description
Flunoxaprofen is an anti-inflammatory drug that is structurally related to the now withdrawn benoxaprofen. It is a potent inhibitor of lipoxygenase, an enzyme involved in the production of inflammatory mediators. This action allows Flunoxaprofen to control inflammation with fewer gastric disturbances compared to other nonsteroidal anti-inflammatory drugs (NSAIDs). It has been found to be effective in the treatment of various inflammatory conditions, including rheumatoid arthritis, myositis, synovitis, and osteoarthritis.
Uses
Used in Pharmaceutical Industry:
Flunoxaprofen is used as an anti-inflammatory agent for the treatment of rheumatoid arthritis, myositis, synovitis, and osteoarthritis. Its lipoxygenase inhibition mechanism allows for effective control of inflammation with reduced risk of gastric disturbances compared to other NSAIDs.
Used in Inflammatory Conditions Treatment:
Flunoxaprofen is used as a therapeutic agent for managing inflammatory conditions, such as rheumatoid arthritis, myositis, synovitis, and osteoarthritis. Its ability to inhibit lipoxygenase helps in reducing inflammation and providing relief from pain and swelling associated with these conditions.
Originator
Ravizza (Italy)
Check Digit Verification of cas no
The CAS Registry Mumber 66934-18-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,9,3 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 66934-18:
(7*6)+(6*6)+(5*9)+(4*3)+(3*4)+(2*1)+(1*8)=157
157 % 10 = 7
So 66934-18-7 is a valid CAS Registry Number.
InChI:InChI=1/C16H12FNO3/c1-9(16(19)20)11-4-7-14-13(8-11)18-15(21-14)10-2-5-12(17)6-3-10/h2-9H,1H3,(H,19,20)/t9-/m0/s1
66934-18-7Relevant articles and documents
-
Dunwell,D.W. et al.
, p. 53 - 58 (1975)
-
Process for preparing benzoxazolyl propionic acid derivatives
-
, (2008/06/13)
The application describes a process for preparing 2-phenyl derivatives of benzoxazolyl propionic acid of formula STR1 in which X is H, Cl, Br, F, or a linear or branched alkyl or 1 to 6 carbon atoms. The process starts from 3-nitro-4-hydroxyphenyl-α-methy
Anti-inflammatory 1,2-benzisoxazole derivatives
-
, (2008/06/13)
3-Phenyl substituted 1,2-benzisoxazole acetic and propionic acid derivatives with anti-inflammatory activity.