66938-29-2

Basic information

• Product Name: 2-FLUORO-4'-METHOXYBENZOPHENONE
• Synonyms: 2-FLUORO-4'-METHOXYBENZOPHENONE;LABOTEST-BB LT00454689
• CAS NO: 66938-29-2
• Molecular Formula: C₁₄H₁₁FO₂
• Molecular Weight: 230.23
• EINECS: -0
• Product Categories: Aromatic Benzophenones & Derivatives (substituted)
• Mol File: 66938-29-2.mol
• Article Data: 13

Chemical Properties

• Melting Point: 55-57°C
• Boiling Point: 155-160°C 5mm
• Flash Point: 155-160°C/5mm
• Appearance: /
• Density: 1.176 g/cm³
• BRN: 2107951
• CAS DataBase Reference: 2-FLUORO-4'-METHOXYBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUORO-4'-METHOXYBENZOPHENONE(66938-29-2)
• EPA Substance Registry System: 2-FLUORO-4'-METHOXYBENZOPHENONE(66938-29-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 66938-29-2(Hazardous Substances Data)

Usage

General Description

2-Fluoro-4'-methoxybenzophenone is a chemical compound with the molecular formula C14H11FO2. It is a member of the benzophenone family and is commonly used as a building block in the synthesis of pharmaceuticals and organic compounds. 2-FLUORO-4'-METHOXYBENZOPHENONE is characterized by its benzophenone core structure, which consists of two benzene rings connected by a ketone group. The presence of a fluorine atom at the 2 position and a methoxy group at the 4' position of one of the benzene rings gives this compound its unique chemical properties. It is often used as a photoinitiator in the manufacturing of various types of polymers and resins, and it has potential applications in the pharmaceutical industry due to its ability to modulate biological processes.

Upstream product

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Downstream Products

• 1451489-90-9 3-(4-methoxyphenyl)-1,2-dimethyl-2,3-dihydro-1H-indazole 
• 55271-06-2 3-(4-methoxyphenyl)-1H-indazole 
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Relevant articles and documents

Tetra- And Dinuclear Palladium Complexes Based on a Ligand of 2,8-Di-2-pyridinylanthyridine: Preparation, Characterization, and Catalytic Activity

Complexation of L [L = 5-phenyl-2,8-di-2-pyridinyl-anthyridine] with [Pd(CH3CN)4](BF4)2 and [Pd(CH3CN)3Cl](BF4) in a molar ratio of 1:2 rendered the corresponding dinuclear complexes [Pd2L (CH3CN)4](BF4)4 (1) and [Pd2L (CH3CN)2Cl2](BF4)2 (2), respectively. However, treatment of L with (COD)PdCl2 followed by anion exchange yielded a tetranuclear complex [Pd4L3Cl4](PF6)4(4a). Structures of these complexes are characterized by both spectroscopy and X-ray crystallography. Interconversion of these three complexes was studied via the manipulation of stoichiometric ratio of ligand to metal precursor. The catalytic activity of these complexes for carbonylative Suzuki-Miyaura cross-coupling was investigated. Complex 2 shows an excellent catalytic activity on the reaction of aryl iodide with arylboronic acid in the presence of atmospheric pressure of CO to give the corresponding benzophenones.

Method of utilizing continuous flow microreactor to synthesize benzophenone derivative

The invention belongs to the technical field of organic synthesis, and particularly relates to a method of utilizing a continuous flow microreactor to synthesize a benzophenone derivative. The methodincludes: using aryl Grignard reagent and acyl chloride as raw materials; at normal temperature, continuously synthesizing the benzophenone derivative in the microreactor; recycling a reaction solvent2-methyl tetrahydrofuran. Problems of environmental pollution and reaction operation safety caused by the fact that conventional Fridel-Crafts reaction is excessively dependent on reagents like aluminum trichloride, ferric trichloride and zinc dichloride are avoided, the defect that novel catalytic processes are expensive in catalytic reagent and harsh in operation condition is made up, and continuous synthesis of a medical intermediate ketoprofen nitrile is realized efficiently. The method has the advantages of high operation convenience, high reaction safety, high yield, high efficiency andreaction solvent reusability and is environment-friendly and efficient.

Erbium trifluoromethanesulfonate catalyzed Friedel-Crafts acylation using aromatic carboxylic acids as acylating agents under monomode-microwave irradiation

Erbium trifluoromethanesulfonate is found to be a good catalyst for the Friedel-Crafts acylation of arenes containing electron-donating substituents using aromatic carboxylic acids as the acylating agents under microwave irradiation. An effective, rapid and waste-free method allows the preparation of a wide range of aryl ketones in good yields and in short reaction times with minimum amounts of waste.