66967-26-8

Basic information

• Product Name: Phenol, 3,4-dimethoxy-2-(2-propenyl)-
• CAS NO: 66967-26-8
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Mol File: 66967-26-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Phenol, 3,4-dimethoxy-2-(2-propenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 3,4-dimethoxy-2-(2-propenyl)-(66967-26-8)
• EPA Substance Registry System: Phenol, 3,4-dimethoxy-2-(2-propenyl)-(66967-26-8)

Safety Data

• Hazardous Substances Data: 66967-26-8(Hazardous Substances Data)

Upstream product

• 2033-89-8 3,4-dimethoxyphenol 
• 6906-64-5 4-(allyloxy)-1,2-dimethoxybenzene 
• 854660-61-0 2-allyloxy-4,5-dimethoxy-benzoic acid methyl ester 
• 28373-21-9 2-hydroxy-4,5-dimethoxybenzoic acid methyl ester 
• 18075-40-6 O-allylisovanillin 
• 18075-41-7 2-allyl-3-hydroxy-4-methoxybenzaldehyde 
• 621-59-0 isovanillin 
• 92345-90-9 3,4-dimethoxy-2-allylbenzaldehyde 
• 412036-15-8 3-allyl-2-hydroxy-4,5-dimethoxy-benzoic acid 
• 121-69-7 N,N-dimethyl-aniline 

Downstream Products

• 501368-18-9 2-allyl-1-allyloxy-3,4-dimethoxybenzene 
• 1194403-17-2 2-(2-allyl-3,4-dimethoxyphenoxy)-1-(4-methoxyphenyl)ethanone 
• 1194403-20-7 2-(2-allyl-3,4-dimethoxyphenoxy)-1-(4-bromophenyl)ethanone 
• 1194403-19-4 2-(2-allyl-3,4-dimethoxyphenoxy)-1-(4-chlorophenyl)ethanone 
• 1194403-18-3 2-(2-allyl-3,4-dimethoxyphenoxy)-1-(p-tolyl)ethanone 
• 1194403-16-1 2-(2-allyl-3,4-dimethoxyphenoxy)-1-phenylethanone 
• 881199-40-2 2-allyl-1-[(2-allyl-3-isopropoxy-4-methoxybenzyl)oxy]-3,4-dimethoxybenzene 
• 881199-39-9 2-allyl-1-[(2-allyl-3-ethoxy-4-methoxybenzyl)oxy]-3,4-dimethoxybenzene 
• 767290-04-0 2-allyl-1-(2-chloroethoxy)-3,4-dimethoxylbenzene 
• 66967-27-9 2-allyl-3,4,4-trimethoxycyclohexa-2,5-dienone 

Relevant articles and documents

Investigating the microwave-accelerated Claisen rearrangement of allyl aryl ethers: Scope of the catalysts, solvents, temperatures, and substrates

The microwave-accelerated Claisen rearrangement of allyl aryl ethers was investigated, in order to gain insight into the scope of the catalysts, solvents, temperatures, and substrates. Among the catalysts examined, phosphomolybdic acid (PMA) was found to greatly accelerate the reaction in NMP, at temperatures ranging from 220 to 300 °C. This method was found to be useful for preparing several intermediates previously reported in the literature using precious metal catalysts such as Au(I), Ag(I), and Pt(II). Additionally, substrates bearing bromo and nitro groups on the aryl portion required careful tailoring of the reaction conditions to avoid complex product profiles.

A new synthesis of substituted 2,5-dihydro[b]-oxepines

Based on Claisen rearrangement, Baeyer-Villiger oxidation, and ring-closing metathesis (RCM), a series of substituted 2,5-dihydrobenzo[b]-oxepines were synthesized from isovanillin in good over-all yields. Other appropriate substituted 2,5-dihydrobenzo[b]oxepines prepared from corresponding phenol derivatives were also described.

The Synthesis of Megaphone

Condensation of 4,4,5-trimethoxy-2-propyl>-2,5-cyclohexadien-1-one (7) with 1,2,3-trimethoxy-5-(1-(Z)-propenyl)benzene in dichloromethane, in the presence of 1 equiv. of stannic chloride, gave (2β,3β,3aα)-3,3a-dihydro-5-methoxy-3-m