66984-23-4Relevant articles and documents
Synthesis and Enzymatic Kinetic Resolution of α,α -Disubstituted Cyclic Hydroxy Nitriles
Levy, Laura M.,Gotor, Vicente
, p. 2601 - 2602 (2007/10/03)
Herein, we describe the diastereoselective synthesis of five- and six-membered α,α-disubstituted cyclic β-hydroxy nitriles and their resolution via enzymatic transesterification. By this method, all possible stereoisomers were obtained in enantiopure form and high yield.
Novel multiaction of Zr catalyst: One-pot synthesis of β-cyanohydrins from olefins [14]
Yamasaki,Kanai,Shibasaki
, p. 1256 - 1257 (2007/10/03)
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Reaction of Cyanotrimethylsilane with Oxiranes. Effect of Catalysts or Mediators on Regioselectivity and Ambident Character
Imi, Katsuharu,Yanagihara, Naoto,Utimoto, Kiitiro
, p. 1013 - 1016 (2007/10/02)
Reaction of cyanotrimethylsilane with oxiranes under the catalytic action of Lewis acids Pd(CN)2, SnCl2, or Me3Ga affords 2-trimethylsiloxy isocyanides by regio- and stereoselective attack of isocyanide on the more substituted carbon.The reaction mediated by aluminium alkoxides gives predominantly 3-trimethylsiloxy nitriles by the selective attack of cyanide on the less substituted carbon.
