66985-49-7

Basic information

• Product Name: 2-(4-methylphenyl)-2-(trimethylsilyloxy)acetonitrile
• Synonyms: 2-(4-methylphenyl)-2-(trimethylsilyloxy)acetonitrile
• CAS NO: 66985-49-7
• Molecular Weight: 219.359
• Mol File: 66985-49-7.mol
• Article Data: 112

Chemical Properties

• CAS DataBase Reference: 2-(4-methylphenyl)-2-(trimethylsilyloxy)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methylphenyl)-2-(trimethylsilyloxy)acetonitrile(66985-49-7)
• EPA Substance Registry System: 2-(4-methylphenyl)-2-(trimethylsilyloxy)acetonitrile(66985-49-7)

Safety Data

• Hazardous Substances Data: 66985-49-7(Hazardous Substances Data)

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 1066-54-2 trimethylsilylacetylene 
• 351-54-2 3-fluoro-p-anisaldehyde 
• 75-77-4 chloro-trimethyl-silane 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 177755-45-2 2-(3-fluoro-4-methoxyphenyl)-2-[(trimethylsilyl)oxy]acetonitrile 
• 7677-24-9 trimethylsilyl cyanide 
• 589-18-4 4-Methylbenzyl alcohol 
• 151-50-8 potassium cyanide 
• 13435-20-6 tetraethylammoniumcyanide 
• 107134-94-1 (4-methylphenyl)<(trimethylsiloxy)methyl>triphenylphosphonium trifluoromethanesulfonate 
• 107134-90-7 1-<(4-Methylphenyl)(trimethylsilyloxy)methyl>pyridinium-trifluormethansulfonat 
• 4648-54-8 trimethylsilylazide 

Downstream Products

• 87712-87-6 (R,R)-(+)-α-<(1-phenylethyl)amino>-α-(p-tolyl)acetonitrile hydrochloride 
• 87712-88-7 (S,S)-(-)-α-<(1-phenylethyl)amino>-α-(p-tolyl)acetonitrile hydrochloride 
• 96824-35-0 (S)-((R)-1-Phenyl-ethylamino)-p-tolyl-acetonitrile; hydrochloride 
• 98405-64-2 2,4,6-Cycloheptatrien-1-yl-(4-methylphenyl)keton 
• 73475-24-8 2-(p-methylphenyl)aziridine 
• 53360-85-3 2-amino-1-(4-methylphenyl)ethanol 
• 1143018-79-4 4,4,5,5-tetramethyl-2-((4-methylbenzyl)oxy)-1,3,2-dioxaborolane 
• 766-97-2 4-n-methylphenylacetylene 
• 1424280-45-4 C₂₇H₄₄O₄Si 
• 1424280-44-3 C₂₇H₄₆O₄Si 
• 1424280-43-2 C₂₄H₄₀O₄Si 
• 119904-34-6 (R)-(-)-1-cyano-1-(4-methylphenyl)methyl acetate 

Relevant articles and documents

Synthesis, Crystal Structure, and Catalytic Properties of Porous 3d-4f Heterometallic Coordination Polymers Constructed from Pyrazine-2,3-dicarboxylic Acid

Reactions of pyrazine-2,3-dicarboxylic acid (H2pzdc), cobalt nitrate and lanthanide (Ln) oxide under hydrothermal conditions result in four new 3d-4f heterometal coordination polymers, namely, [Ln2Co(pzdc)4(H2O)

Cyanosilylation of carbonyl compounds catalyzed by half-sandwich (η6-p-cymene) Ruthenium(II) complexes bearing heterocyclic hydrazone derivatives

A new class of half-sandwich (?6-p-cymene) ruthenium(II) complexes supported by heterocyclic hydrazone derivatives of general formula [Ru(?6-p-cymene)(Cl)(L)] where L represents N’-((1H-pyrrol-2-yl)methylene)furan-2-carbohydrazide (L

Zirconium-based MOF catalyst with double active sites and preparation method and application thereof

The invention discloses a zirconium-based MOF catalyst loaded with double active sites as well as a preparation method and an application of the zirconium-based MOF catalyst. The method comprises thefollowing steps: adding zirconium salt and an organic ligand into an organic solvent, taking organic acid as a regulator, and carrying out self-assembly reaction to obtain a metal organic framework; adding salicylaldehyde for aldehyde amine condensation to obtain chelating coordination sites, adding palladium salt, and performing coordination through an impregnation method; reducing the obtained MOF in hydrogen to obtain an MOF loaded with Pd nanoparticles; reacting MOF and zinc salt in an organic solvent, and obtaining the catalyst. The Pd-Zn-coated UiO-68-NH2-CH3 catalyst synthesized by thepreparation method disclosed by the invention has efficient catalytic activity in a tandem alcohol oxidation/aldehyde cyanosilylation reaction. According to the catalyst, a metal organic framework UiO-68-NH2-CH3 is constructed, Pd nanoparticles and Zn are loaded by taking the metal organic framework UiO-68-NH2-CH3 as a carrier, the loading capacity of the Pd nanoparticles is 4-8wt%, and the loading capacity of the Zn is 3-5wt%.

Three Coordinated Organoaluminum Cation for Rapid and Selective Cyanosilylation of Carbonyls under Solvent-Free Conditions

The well-defined three coordinated electronically unsaturated cationic organoaluminum complex [({(2,6-iPr2C6H3N)P(Ph2)}2N)AlMe]+[MeB(C6F5)3]? (1), has been utilized to catalyze the cyanosilylation of aldehydes and ketones under mild and solvent-free conditions. Moreover, catalyst 1 showed high chemoselective cyanosilylation of aldehydes over ketones, nitriles and olefins. The multinuclear NMR investigations revealed that cyanosilylation proceeds via Lewis adduct formation between 1 and TMSCN thereby activating TMSCN (Si-CN bond) followed by nucleophilic attack of the carbonyl oxygen at the Si center of the activated silane and formation of the product.