67036-49-1

Basic information

• Product Name: isonicotinylamide GABA
• Synonyms: isonicotinylamide GABA
• CAS NO: 67036-49-1
• Molecular Formula: C₁₀H₁₂N₂O₃
• Molecular Weight: 208.216
• Mol File: 67036-49-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 522.4°C at 760 mmHg
• Flash Point: 269.8°C
• Appearance: /
• Density: 1.245g/cm³
• Vapor Pressure: 9.65E-12mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: isonicotinylamide GABA(CAS DataBase Reference)
• NIST Chemistry Reference: isonicotinylamide GABA(67036-49-1)
• EPA Substance Registry System: isonicotinylamide GABA(67036-49-1)

Safety Data

• Hazardous Substances Data: 67036-49-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12N2O3/c13-9(14)2-1-5-12-10(15)8-3-6-11-7-4-8/h3-4,6-7H,1-2,5H2,(H,12,15)(H,13,14)

Upstream product

• 54-85-3 isoniazid 
• 4013-73-4 isonicotinoyl azide 
• 56-12-2 4-amino-n-butyric acid 

Downstream Products

• 55-22-1 pyridine-4-carboxylic acid 
• 56-12-2 4-amino-n-butyric acid 

Relevant articles and documents

Fluoroquinolone such amino derivative and use thereof (by machine translation)

The invention belongs to the field of pharmaceutical chemistry, and in particular relates to a fluoroquinolone derivatives and use thereof. The invention through structural modification of the fluoroquinolone drugs such as shown in formula I, the compounds of the invention not only can the Mycobacterium tuberculosis and the normal bacterial caused by the treatment of infection, bacteria also holds keeps the fungus, citrus pathogens, nicotinamide N - methyltransferase (NNMT) and interleukin IL - 17 PPI has inhibitory activity. The compounds of the invention preparation process operation is convenient, mild condition, to obtain the antibacterial activity is enhanced, water-soluble improve, many compounds toxic side effects, it is expected to reduce the amount of medicine used, shorten the treatment cycle, improve patient's compliance, for tuberculosis drug and other disease research provide new molecular type with the study. (by machine translation)

Evaluation of isonicotinoyl-γ-aminobutyric acid (GABA) nicotinoyl-GABA as pro-drugs of GABA

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