67049-95-0

Basic information

• Product Name: OXIBENDAZOLE
• Synonyms: N-(5-Propoxy-2H-benzimidazol-2-yl)carbamic acid methyl ester
• CAS NO: 67049-95-0
• Molecular Formula: C12H15N3O3
• Molecular Weight: 0
• Mol File: 67049-95-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.3g/cm³
• Refractive Index: 1.596
• CAS DataBase Reference: OXIBENDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: OXIBENDAZOLE(67049-95-0)
• EPA Substance Registry System: OXIBENDAZOLE(67049-95-0)

Safety Data

• Hazardous Substances Data: 67049-95-0(Hazardous Substances Data)

Usage

Safety Profile

Poison by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.See also CARBAMATES and ESTERS

InChI:InChI=1/C12H15N3O3/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7,11H,3,6H2,1-2H3,(H,15,16)

Upstream product

• 420-04-2 CYANAMID 
• 56190-17-1 4-n-propoxy-o-phenylenediamine 
• 79-22-1 methyl chloroformate 

Relevant articles and documents

2H-benzimidazoles (isobenzimidazoles). Part 10. Synthesis of polysubstituted o-phenylenediamines and their conversion into heterocycles, particularly 2-substituted benzimidazoles with known or potential anthelminthic activity

Polysubstituted o-phenylenediamines were synthesised in moderate to high yield by reductive cleavage of the corresponding 2H-benzimidazole-2-spirocyclohexane with sodium dithionite in aqueous ethanol and converted into methyl benzimidazole-2-carbamates and 2-methylthio- and 2-trifluoro-methylbenzimidazoles with known or potential anthelminthic activity. 5-(Pyrimidin-2-ylthio)-benzimidazole and 11-(pyridin-2-ylthio)dibenzo[a,c]phenazine were synthesized too. Attempts to oxidise 1,3-dihydro-2H-4,9-diazanaphth[2,3-d]imidazole, prepared by condensation of 2,3-diaminoquinoxaline with cyclohexanone, to an analogue of the title system failed.