671-19-2

Basic information

• Product Name: (E)-α-Fluorostilbene
• Synonyms: (E)-1-Fluoro-1,2-diphenylethene;(E)-α-Fluorostilbene
• CAS NO: 671-19-2
• Molecular Formula: C₁₄H₁₁F
• Molecular Weight: 198.24
• Mol File: 671-19-2.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-α-Fluorostilbene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-α-Fluorostilbene(671-19-2)
• EPA Substance Registry System: (E)-α-Fluorostilbene(671-19-2)

Safety Data

• Hazardous Substances Data: 671-19-2(Hazardous Substances Data)

Upstream product

• 345-82-4 1,2-difluoro-1,2-diphenylethane 
• 501-65-5 diphenyl acetylene 
• 100-52-7 benzaldehyde 
• 57266-93-0 ((E)-1,2-diphenylvinyl)trimethylsilane 
• 645-49-8 cis-stilben 
• 530-48-3 1,1-Diphenylethylene 
• 1663-55-4 diethyl [hydroxy(phenyl)methyl]phosphonate 
• 71370-23-5 1-chloro-2-fluoro-1,2-diphenylethane 
• 75-05-8 acetonitrile 
• 64-17-5 ethanol 
• 724-66-3 α'-bromo-α,α-difluoro-bibenzyl 
• 350-62-9 1,1-difluoro-1,2-diphenylethane 
• 960-16-7 tributylphenylstannane 
• 88410-05-3 (Z)-β-bromo-β-fluorostyrene 

Relevant articles and documents

Stereodivergent Alkyne Hydrofluorination Using Protic Tetrafluoroborates as Tunable Reagents

The discovery of safe, general, and practical procedures to prepare vinyl fluorides from readily available precursors remains a synthetic challenge. The metal-free hydrofluorination of alkynes constitutes an attractive though elusive strategy for their preparation. Introduced here is an inexpensive and easily handled reagent that enables the development of simple and scalable protocols for the regioselective hydrofluorination of alkynes to access both the E and Z isomers of vinyl fluorides. These reaction conditions were suitable for a diverse collection of alkynes, including several highly functionalized pharmaceutical derivatives. Computational and experimental mechanistic studies support C?F bond formation through vinyl cation intermediates, with the E- and Z-hydrofluorination products forming under kinetic and thermodynamic control, respectively.

Geminal difunctionalization of α-diazo arylmethylphosphonates: Synthesis of fluorinated phosphonates

A general approach towards diverse fluorinated phosphonates via geminal difunctionalization reactions of α-diazo arylmethylphosphonates is described. The diazo functionality (RR′CN2) is successfully converted to RR′CF2, RR′CHF, RR′CFBr or RR′CFNR′′2 groups by employing different fluorination reagents. A variety of fluorinated organophosphorus compounds were readily accessed in good to excellent yields from a common type of precursor.

Acceleration of alkenyltrimethylsilane fluorination under mild conditions using ultrasound

Alkenyltrimethylsilanes are selectively fluorodesilated to alkenyl fluoride very readily by reaction with 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2,2,2]octane bis-tetrafluoroborate (Selectfluor) and N-fluorobenzensulfonimids at room temperature under