67173-16-4

Basic information

• Product Name: 2-(3-chloro-phenyl)-2-phenyl-[1,3]dioxolane
• Synonyms: 2-(3-chloro-phenyl)-2-phenyl-[1,3]dioxolane
• CAS NO: 67173-16-4
• Molecular Weight: 260.72
• Mol File: 67173-16-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-chloro-phenyl)-2-phenyl-[1,3]dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-chloro-phenyl)-2-phenyl-[1,3]dioxolane(67173-16-4)
• EPA Substance Registry System: 2-(3-chloro-phenyl)-2-phenyl-[1,3]dioxolane(67173-16-4)

Safety Data

• Hazardous Substances Data: 67173-16-4(Hazardous Substances Data)

Upstream product

• 1016-78-0 3-chlorobenzophenone 
• 107-21-1 ethylene glycol 

Downstream Products

• 1003006-93-6 C₁₆H₁₃ClO₄ 

Relevant articles and documents

Lithiation of 2-aryl-2-(chloroaryl)-1,3-dioxolanes and its application in the synthesis of new ortho-functionalized benzophenone derivatives

2-Aryl-2-(chloroaryl)-1,3-dioxolanes 4 were lithiated ortho to the ketal group of the chloroaryl ring by treatment with butyllithium in THF between -78 and 0°C. The site selectivity of some of the deprotonation reactions was rationalized by the long-range effect of the 4-chloro substituent. The lithio species thus generated were treated with various electrophiles to give ortho-functionalized benzophenone derivatives. Intramolecular competition between the aryl rings was observed in the lithiation of 2-(4-chlorophenyl)-2- (4-fluorophenyl)-1,3-dioxolane (4s). Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.