671779-99-0Relevant articles and documents
GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES
-
, (2015/04/15)
Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).
Synthesis of 7-substituted-(2,3-dihydro-1,4-benzodioxin-5-yl)-piperazine
Rancati, Fabio,Bromidge, Steven M.,Del Sordo, Simone,La Rosa, Salvatore,Parini, Carlo,Gagliardi, Stefania
, p. 2507 - 2520 (2008/12/22)
A simple and versatile method for the synthesis of 7-substituted (2,3-dihydro-1,4-benzodioxin-5-yl)-piperazines starting from easy available class of derivatives has been developed. Copyright Taylor & Francis Group, LLC.
Total synthesis of the marine alkaloid halitulin
Heinrich, Markus R.,Steglich, Wolfgang,Banwell, Martin G.,Kashman, Yoel
, p. 9239 - 9247 (2007/10/03)
The structure of the strongly cytotoxic marine alkaloid halitulin (1) has been confirmed by total synthesis and its absolute configuration determined as (15S). The synthesis follows a strategy previously reported by one of us and uses an efficient prepara
