67198-21-4 Usage
Description
1,2-Cyclohexanediamine, N,N-dimethyl-, transis a chiral amine compound characterized by its trans-configuration. It is known for its ability to act as a catalyst in various chemical reactions, particularly in asymmetric direct aldol and Michael addition reactions. This unique property makes it a valuable component in the synthesis of complex organic molecules and pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
1,2-Cyclohexanediamine, N,N-dimethyl-, transis used as a chiral amine catalyst for enhancing the selectivity and efficiency of asymmetric direct aldol and Michael addition reactions. This application is crucial in the synthesis of enantiomerically pure compounds, which are essential in the development of many pharmaceutical drugs. The use of this catalyst allows for the production of these compounds with higher yields and better enantioselectivity, ultimately leading to more effective and safer medications.
Used in Chemical Synthesis:
In the field of chemical synthesis, 1,2-Cyclohexanediamine, N,N-dimethyl-, transis used as a chiral amine catalyst to facilitate asymmetric reactions. This is particularly important in the synthesis of complex organic molecules, such as natural products and biologically active compounds. The use of this catalyst can improve the overall yield and selectivity of these reactions, making it a valuable tool for chemists working in various research and development settings.
Used in Research and Development:
1,2-Cyclohexanediamine, N,N-dimethyl-, transis also utilized in research and development laboratories for the study of asymmetric catalysis and the development of new synthetic methods. Its unique properties make it an attractive candidate for exploring novel reaction mechanisms and designing innovative catalysts for various chemical transformations. This can lead to the discovery of new synthetic routes and the development of more efficient and environmentally friendly processes in the chemical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 67198-21-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,1,9 and 8 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 67198-21:
(7*6)+(6*7)+(5*1)+(4*9)+(3*8)+(2*2)+(1*1)=154
154 % 10 = 4
So 67198-21-4 is a valid CAS Registry Number.
67198-21-4Relevant articles and documents
Synthesis, resolution, and absolute configuration of trans-1-amino-2-dimethylaminocyclohexane
Christoffers, Jens,Schulze, Yvonne,Pickardt, Joachim
, p. 1765 - 1769 (2007/10/03)
Racemic trans-1-amino-2-dimethylaminocyclohexane was prepared by aziridine ring opening reaction of 7-azabicyclo[4.1.0]heptane with HNMe2. The resolution of the racemate was accomplished by crystallization as the L-tartrate. The optical purity
Analgesic N-[2-(furyl-methylamino and 2-thienylmethylamino)cycloaliphatic]be
-
, (2008/06/13)
Cis - and trans-N-(2-aminocycycloaliphatic)benzamide compounds of the formula STR1 e.g., N-methyl-N-[2-[(2-furylmethyl)methylamino]-cyclohexyl]-3,4-dichlorobenzamide, and their pharmaceutically acceptable salts, have been found to have potent analgesic activity, and compositions containing these compounds useful in pharmaceutical dosage unit form for alleviating pain in warm-blooded animals, as well as methods for alleviating pain in animals with these compositions. Processes for preparing the compounds are also disclosed.
