672326-01-1

Basic information

• Product Name: Thieno[2,3-b]pyridine-5-carboxamide, 2-(chloromethyl)-N-[(4-chlorophenyl)methyl]-4,7-dihydro-7-methyl-4-oxo-
• CAS NO: 672326-01-1
• Molecular Formula: C17H14Cl2N2O2S
• Molecular Weight: 381.282
• Mol File: 672326-01-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Thieno[2,3-b]pyridine-5-carboxamide, 2-(chloromethyl)-N-[(4-chlorophenyl)methyl]-4,7-dihydro-7-methyl-4-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: Thieno[2,3-b]pyridine-5-carboxamide, 2-(chloromethyl)-N-[(4-chlorophenyl)methyl]-4,7-dihydro-7-methyl-4-oxo-(672326-01-1)
• EPA Substance Registry System: Thieno[2,3-b]pyridine-5-carboxamide, 2-(chloromethyl)-N-[(4-chlorophenyl)methyl]-4,7-dihydro-7-methyl-4-oxo-(672326-01-1)

Safety Data

• Hazardous Substances Data: 672326-01-1(Hazardous Substances Data)

Upstream product

• 292144-10-6 PNU-243672 
• 292144-09-3 N-(4-chlorobenzyl)-2-(hydroxymethyl)-7-methyl-4-oxo-4,7-dihydrothieno[2,3-b]-pyridine-5-carboxamide 

Downstream Products

• 292144-13-9 rac-N-(4-chlorobenzyl)-2-(((2-hydroxy-2-(4-hydroxyphenyl)ethyl)(methyl)amino)methyl)-7-methyl-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamide 
• 672949-12-1 rac-N-(4-chlorobenzyl)-2-(((2-hydroxy-2-(pyridin-3-yl)ethyl)(methyl)amino)methyl)-7-methyl-4-oxo-4,7-dihydrothieno[2,3-b]-pyridine-5-carboxamide 
• 672326-40-8 C₂₇H₂₅N₄SO₃Cl 
• 672326-39-5 C₂₇H₂₅N₄SO₃Cl 

Relevant articles and documents

2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases

A novel series of 2-aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides have been identified as potent antivirals against human herpesviruses. These compounds demonstrate broad-spectrum inhibition of the herpesvirus polymerases HCMV, HSV-1, EBV, and VZV with high specificity compared to human DNA polymerases.

4-OXO-4,7-DIHYDROTHIENO[2,3-b]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS

The present invention provides a compound of a formula (I) as described herein, which are useful as antiviral agents, in particular, as agents againts viruses of the herpes family.

ARYL-ETHANOLAMINE DERIVATIVES AS ANTIVIRAL AGENTS

The present invention provides a compound of formula as describedherein, which are useful as antiviral agents, in particular, as agents against viruses of the herpes family.