67249-24-5Relevant articles and documents
AMIDOETHYL AZOLE OREXIN RECEPTOR ANTAGONISTS
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Page/Page column 34-35, (2016/07/27)
An amidoethyl azole compounds are provided as antagonists of orexin receptors. The compounds may be used for treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved.
Synthesis of two metabolites of the antiarrythmicum amiodarone
Wendt, Barbara,Ha, Huy Riem,Hesse, Manfred
, p. 2990 - 3001 (2007/10/03)
The metabolism of the potent antiarrythmic drug amiodarone (AMI; 1) has yet not been fully investigated. Recently, in vitro experiments revealed that in rabbit-liver microsomes, AMI (1) and its main metabolite MDEA (2) were biotransformed to the hydroxyla