67253-47-8Relevant articles and documents
Enantioselective cross-coupling of meso -epoxides with aryl halides
Zhao, Yang,Weix, Daniel J.
supporting information, p. 3327 - 3340 (2015/03/30)
The first enantioselective cross-electrophile coupling of aryl bromides with meso-epoxides to form trans-β-arylcycloalkanols is presented. The reaction is catalyzed by a combination of (bpy)NiCl2 and a chiral titanocene under reducing conditions. Yields range from 57 to 99% with 78-95% enantiomeric excess. The 30 examples include a variety of functional groups (ether, ester, ketone, nitrile, ketal, trifluoromethyl, sulfonamide, sulfonate ester), both aryl and vinyl halides, and five- to seven-membered rings. The intermediacy of a carbon radical is strongly suggested by the conversion of cyclooctene monoxide to an aryl [3.3.0]bicyclooctanol.
Enzymatic kinetic resolution of organochalcogenides in supercritical CO2
Gariani, Rogério A.,Luengo, Fernando A.G.,Vale, Luiz A.S.,Bazito, Reinaldo C.,Comasseto, Jo?o V.
supporting information; experimental part, p. 3336 - 3338 (2011/06/28)
1-(Phenylthio)-, 1-(phenylseleno)- and 1-(phenyltelluro)-propan-2-ol were efficiently resolved by CAL-B in sc-CO2.
Stereoinversion of arylethanols by Geotrichum candidum
Nakamura, Kaoru,Fujii, Mikio,Ida, Yoshiteru
, p. 3147 - 3153 (2007/10/03)
Aromatic and aliphatic racemic alcohols were converted to the corresponding optically active alcohols in high yield with excellent enantioselectivities by the use of Geotrichum candidum IFO 5767.