67278-70-0Relevant articles and documents
Reaction of Trimetaphosphate with Glycine
Tsuhako, Mitsumoto,Ohashi, Shigeru,Nariai, Hiroyuki,Motooka, Itaru
, p. 3882 - 3889 (2007/10/02)
The reaction of trimetaphosphate (P3m) with glycine in an aqueous solution was studied. 1) P3m reacted with glycine at pH 10 and above to form two unknown compounds, A and B. 2) The amounts of these compounds were strongly affected by reaction conditions, such as the mixing ratio of P3m and glycine and the pH, and the yields of compounds A and B were around 26 and 24 percent, respectively. 3) Compound A was proved to be an orthophosphate derivative of glycine (P1-derivative of glycine), aminoacetyl phosphate, , while compound B was found to be a P1-derivative of glycine, N-(carboxymethyl)phosphoramidate, . 4) It was found that glycilglycine (dimer), glycilglycilglycine (trimer), and higher oligopeptides of glycine were formed in the reaction of P3m and glycine.Further, in the reaction at pH 10-14, tetra- (P4) and pentaphosphate (P5) were also formed besides compounds A and B, though in small quantities. 5) Short-chain phosphates, such as ortho-(P1), pyro-(P2) and triphosphate (P3), did not react with glycine at all. 6) The mechanism of the reaction of P3m with glycine is discussed.KEYWORDS-trimetaphosphate; glycine; aminoacetylphosphate; N-(carboxymethyl)phosphoroamidate; phosphorylation
