673-31-4 Usage
Description
Phenprobamate, also known as 3-phenylpropylcarbamate, is a centrally acting muscle relaxant that belongs to the benzene family. It is characterized by its white shiny crystalline appearance, with a melting point of 101-104°C. Phenprobamate is soluble in ethanol, chloroform, propylene glycol, and ethylenediamine, slightly soluble in ether, and almost insoluble in water. It has an odorless, slightly bitter taste, and a slightly numb sensation.
Uses
Used in Pharmaceutical Industry:
Phenprobamate is used as a muscle relaxant for its ability to relieve muscle spasms and pain. It is particularly effective in treating conditions that involve muscle stiffness and discomfort, such as back pain, muscle strains, and sprains.
Phenprobamate is also used as a sedative due to its mild sedative effects, which can help in calming patients and promoting relaxation.
Additionally, Phenprobamate is used as an anticonvulsant for its ability to prevent and control seizures, making it a valuable asset in the treatment of epilepsy and other seizure disorders.
Used in Narcotic Drug Enhancement:
Phenprobamate is used as an enhancer for narcotic drugs, as it can prolong and enhance their effects. This allows for the use of smaller amounts of alcohol or illicit substances to achieve the desired effect, potentially reducing the risk of overdose and addiction.
Safety Profile
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Used as a tranquilizer and muscle relaxant. When heated to decomposition it emits toxic fumes of NOx. See also CARBAMATES and ESTERS
Check Digit Verification of cas no
The CAS Registry Mumber 673-31-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,7 and 3 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 673-31:
(5*6)+(4*7)+(3*3)+(2*3)+(1*1)=74
74 % 10 = 4
So 673-31-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H13NO2/c11-10(12)13-8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H2,11,12)
673-31-4Relevant articles and documents
Further development of the tin-catalyzed transcarbamoylation reaction
Hasegawa, Tomoyuki,Ichikawa, Yoshiyasu,Masuda, Toshiya,Minami, Takahiro,Morishita, Yukinori,Ochi, Rika,Sato, Hiroshi
supporting information, p. 2373 - 2378 (2020/08/19)
Studies carried out to further develop tin-catalyzed trans-carbamoylation reactions demonstrated that transcarbamoylation of cinnamyl alcohol in the context of allyl cyanate-to-isocyanate rearrangement can be efficiently carried out on a ten-gram scale and that tin-catalyzed transcarbamoylation is a valuable alternative to the method using trichloroacetyl isocyanate. In addition, methyl carbamate was found to be an economical carabamoyl donor in tin-catalyzed transcarbamoylation, which showed broad functional group tolerance and allowed a streamlined workup procedure. Finally, a unique synthetic method was developed for the preparation of carbamate-tethered terpene glycoconjugates.
Copper-catalyzed intramolecular C-H amination
Barman, Dipti N.,Nicholas, Kenneth M.
, p. 908 - 911 (2011/04/26)
The amino-functionalization of tertiary, secondary and benzylic C-H bonds of tethered carbamates and sulfamates by iodosobenzene is catalyzed by Cu I-diimine complexes in moderate to good yield. Employing homochiral imine-Cucatalysts affords oxazolidinones and oxathiazinanes with modest enantioselectivity.
Quantitative structure-activity relationships of anticonvulsant aralkyl and alkyl carbamates
Tanaka,Horisaka,Yamagami,Takao,Fujita
, p. 2403 - 2410 (2007/10/02)
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