67341-08-6

Basic information

• Product Name: Carbamic acid, (2-hydroxy-2-phenylethyl)-, phenylmethyl ester
• CAS NO: 67341-08-6
• Molecular Formula: C16H17NO3
• Molecular Weight: 271.316
• Mol File: 67341-08-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Carbamic acid, (2-hydroxy-2-phenylethyl)-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (2-hydroxy-2-phenylethyl)-, phenylmethyl ester(67341-08-6)
• EPA Substance Registry System: Carbamic acid, (2-hydroxy-2-phenylethyl)-, phenylmethyl ester(67341-08-6)

Safety Data

• Hazardous Substances Data: 67341-08-6(Hazardous Substances Data)

Upstream product

• 1499-00-9 2-phenylaziridine 
• 100-42-5 styrene 
• 64420-86-6 O-p-toluenesulfonyl benzyloxyhydroxamate 
• 556-82-1 3-methyl-2-buten-1-ol 
• 95-13-6 1-indene 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 3426-71-9 Benzyl N-hydroxycarbamate 
• 1262306-22-8 benzyloxycarbonylamino-4-chlorobenzoate 
• 54043-04-8 (N-(Benzyloxycarbonyl)amino)-methyl phenyl ketone 
• 96-09-3 styrene oxide 
• 501-53-1 benzyl chloroformate 
• 7568-93-6 2-Amino-1-phenylethanol 
• 91174-01-5 sodium [(benzyloxy)carbonyl]chloroamide 
• 100-52-7 benzaldehyde 

Downstream Products

• 144315-91-3 Butyric acid (R)-2-benzyloxycarbonylamino-1-phenyl-ethyl ester 
• 144315-91-3 Butyric acid (S)-2-benzyloxycarbonylamino-1-phenyl-ethyl ester 
• 500763-83-7 (S)-(+)-(2-hydroxy-2-phenyl-ethyl)-carbamic acid benzyl ester 
• 144372-50-9 (R)-benzyl N-(2-hydroxy-2-phenylethyl)carbamate 
• 2549-14-6 (R)-2-Amino-1-phenylethanol 
• 56613-81-1 (S)-2-Amino-1-phenyl-1-ethanol 
• 4430-27-7 2-amino-1-phenylethane-1-sulfonic acid 
• 678166-60-4 2-(benzyloxycarbonyl)amino-1-phenylethyl thioacetate 

Relevant articles and documents

Novel triazole-based ligands and their zinc(II) and nickel(II) complexes with a nitrogen donor environment as potential structural models for mononuclear active sites

Three new 1,2,3-triazole-based ligands with an N,N,N coordination core were prepared using a convergent synthetic protocol starting from racemic 2-amino-1-phenylethanol. They were tested as chelators for biorelevant ZnII or NiII ions. An N,N,N ligand with a terminal amino functionality coordinated the ZnII in a bidentate fashion, not including the triazole nitrogen. The ligand with two pendant 2-pyridyl groups acted as a tridentate ligand without an N2-triazole coordination to ZnII, while the ligand containing one 2-pyridyl group acted as an inverse-click chelator for NiII ions.

Direct catalytic synthesis of unprotected 2-amino-1-phenylethanols from alkenes by using iron(II) phthalocyanine

Aryl-substituted amino alcohols are privileged scaffolds in medicinal chemistry and natural products. Herein, we report that an exceptionally simple and inexpensive FeII complex efficiently catalyzes the direct transformation of simple alkenes into unprotected amino alcohols in good yield and perfect regioselectivity. This new catalytic method was applied in the expedient synthesis of bioactive molecules and could be extended to aminoetherification.

Osmium-catalyzed vicinal oxyamination of alkenes by N-(4- toluenesulfonyloxy)carbamates

N-(4-Toluenesulfonyloxy)carbamates based on a range of common amine protecting groups serve as preformed nitrogen sources in the intermolecular osmium-catalyzed oxyamination reaction of a variety of mono-, di-, and trisubstituted alkenes. The reactions occur with low catalyst loadings and good yields and afford high regioselectivity for unsymmetrically substituted alkenes.