67387-77-3

Basic information

• Product Name: Benzeneacetonitrile, a-hydroxy-4-methoxy-3-(phenylmethoxy)-
• CAS NO: 67387-77-3
• Molecular Formula: C16H15NO3
• Molecular Weight: 269.3
• Mol File: 67387-77-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzeneacetonitrile, a-hydroxy-4-methoxy-3-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetonitrile, a-hydroxy-4-methoxy-3-(phenylmethoxy)-(67387-77-3)
• EPA Substance Registry System: Benzeneacetonitrile, a-hydroxy-4-methoxy-3-(phenylmethoxy)-(67387-77-3)

Safety Data

• Hazardous Substances Data: 67387-77-3(Hazardous Substances Data)

Upstream product

• 151-50-8 potassium cyanide 
• 7677-24-9 trimethylsilyl cyanide 
• 6346-05-0 3-benzyloxy-4-methoxybenzaldehyde 

Downstream Products

• 125771-56-4 Acetic acid 2-[acetyl-(2-iodo-benzyl)-amino]-1-(5-benzyloxy-2-iodo-4-methoxy-phenyl)-ethyl ester 
• 125771-53-1 O-acetyl-β-(5-benzyloxy-2-iodo-4-methoxyphenyl)-N-(2-iodobenzyl)-N-methylethanolamine 
• 125771-54-2 Acetic acid 2-(benzyl-methyl-amino)-1-(5-benzyloxy-2-iodo-4-methoxy-phenyl)-ethyl ester 
• 125771-65-5 8-acetoxy-10-benzyloxy-11-methoxy-6-methyl-5,6,7,8-tetrahydrodibenzazocine 
• 125771-62-2 5-(5-Benzyloxy-2-iodo-4-methoxy-phenyl)-3-(2-iodo-benzyl)-oxazolidine 
• 125771-55-3 Acetic acid 2-(benzyl-methyl-amino)-1-(3-benzyloxy-4-methoxy-phenyl)-ethyl ester 
• 125771-52-0 β-(5-benzyloxy-2-iodo-4-methoxyphenyl)-N-(2-iodobenzyl)-N-methylethanolamine 
• 125771-51-9 β-(5-benzyloxy-2-iodo-4-methoxyphenyl)-N-(2-iodobenzyl)ethanolamine 
• 125771-68-8 10-benzyloxy-8-hydroxy-11-methoxy-6-methyl-5,6,7,8-tetrahydrodibenzazocine 
• 125771-59-7 N-[2-(5-Benzyloxy-2-iodo-4-methoxy-phenyl)-2-hydroxy-ethyl]-formamide 
• 125771-41-7 β-(5-benzyloxy-2-iodo-4-methoxyphenyl)ethanolamine 
• 78004-26-9 N-<2-Hydroxy-2-(3-benzyloxy-4-methoxyphenyl)ethyl>formamide 
• 52805-37-5 3-benzyloxy-4-methoxybenzonitrile 
• 97798-37-3 3-Benzyloxy-4-methoxybenzoyl cyanide 

Relevant articles and documents

Ruthenium-Catalyzed Oxidations of Alcohols

A combination of low-valent ruthenium complexes and peroxides such as t-BuOOH and peracids serves as efficient catalytic systems for the oxidation of aromatic and aliphatic hydroxy compounds. The utility of these methods was demonstrated by the synthesis of acyl cyanides which are versatile synthetic intermediates. The principle of the catalytic oxidations with peracids lead to the novel and efficient method for aerobic oxidation of alcohols in the presence of aldehydes. This reaction is of importance in synthetic and large scale industrial processes and from environmental points of view. The present principle will provide new chemistry of oxidative transformations of various industrially important functional materials.

RUTHENIUM CATALYZED OXIDATION OF CYANOHYDRINS TO ACYL CYANIDES USEFUL REAGENTS FOR SELECTIVE N-BENZOYLATION OF AMINOALCOHOLS

Ruthenium catalyzed oxidation of cyanohydrins with tert-butyl hydroperoxide gives the corresponding acyl cyanides in good to excellent yields.Acyl cyanides thus obtained are useful reagents for selective N-benzoylation of aminoalcohols.