674776-54-6 Usage
Description
4-(P-TOLUENESULFONYLAMINO)PHENYLBORONIC ACID PINACOL ESTER, 97% is a high-purity boronic acid derivative commonly used in organic synthesis. It features a pinacol ester group that provides stability and enhances reactivity in various chemical reactions, making it a valuable reagent for researchers and organic chemists in the field of chemical synthesis.
Used in Pharmaceutical Industry:
4-(P-TOLUENESULFONYLAMINO)PHENYLBORONIC ACID PINACOL ESTER, 97% is used as an intermediate in the synthesis of pharmaceutical compounds for its ability to participate in various organic reactions, including Suzuki-Miyaura coupling and other catalytic processes.
Used in Chemical Research:
4-(P-TOLUENESULFONYLAMINO)PHENYLBORONIC ACID PINACOL ESTER, 97% is used as a research reagent for studying and developing new synthetic pathways and methodologies in organic chemistry, due to its reactivity and stability in different reaction conditions.
Used in Material Science:
4-(P-TOLUENESULFONYLAMINO)PHENYLBORONIC ACID PINACOL ESTER, 97% is used as a precursor in the development of new materials, such as polymers and composites, where its reactivity and boronic acid functionality can be exploited to create novel structures and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 674776-54-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,4,7,7 and 6 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 674776-54:
(8*6)+(7*7)+(6*4)+(5*7)+(4*7)+(3*6)+(2*5)+(1*4)=216
216 % 10 = 6
So 674776-54-6 is a valid CAS Registry Number.
InChI:InChI=1/C19H24BNO4S/c1-14-6-12-17(13-7-14)26(22,23)21-16-10-8-15(9-11-16)20-24-18(2,3)19(4,5)25-20/h6-13,21H,1-5H3
674776-54-6Relevant articles and documents
Au(i)/Au(iii)-Catalyzed C-N coupling
Rodriguez, Jessica,Adet, Nicolas,Saffon-Merceron, Nathalie,Bourissou, Didier
supporting information, p. 94 - 97 (2019/12/25)
Cycling between Au(i) and Au(iii) is challenging, so gold-catalyzed cross-couplings are rare. The (MeDalphos)AuCl complex, which we showed was prone to undergo oxidative addition, is reported here to efficiently catalyze the C-N coupling of aryl iodides and amines. The transformation does not require an external oxidant or a directing group. It is robust and works with a wide scope of aryl iodides and N-nucleophiles under mild conditions. Mechanistic studies, including the NMR and MS characterization of a key aryl amido Au(iii) complex, strongly support a 2e redox cycle in which oxidative addition precedes transmetalation and reductive elimination is the rate-determining step.
2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION
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Page/Page column 74, (2010/11/30)
A 2,3,4,5-tetrahydro-1H-1,5-benzodiazepine derivative represented by the generalformula (1): [Chemical formula 1] (1) or a pharmaceutically acceptable saltthereof. They are useful as a therapeutic/preventive agent for diabetes, diabeticnephropathy, or glomerulosclerosis.
