674793-32-9

Basic information

• Product Name: 5-chloro-2-fluorobenzamidine
• Synonyms: 5-chloro-2-fluorobenzimidamide hydrochloride;BenzenecarboxiMidaMide, 5-chloro-2-fluoro-;5-chloro-2-fluoroBenzenecarboximidamide;5-chloro-2-fluorobenzamidine;5-chloro-2-fluorobenzimidamide;2-Fluoro-5-chlorobenzamidine
• CAS NO: 674793-32-9
• Molecular Formula: C₇H₆ClFN₂
• Molecular Weight: 172.59
• Mol File: 674793-32-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 255℃
• Flash Point: 108℃
• Appearance: /
• Density: 1.41
• Vapor Pressure: 0.017mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: 5-chloro-2-fluorobenzamidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-fluorobenzamidine(674793-32-9)
• EPA Substance Registry System: 5-chloro-2-fluorobenzamidine(674793-32-9)

Safety Data

• Hazardous Substances Data: 674793-32-9(Hazardous Substances Data)

Usage

General Description

5-chloro-2-fluorobenzamidine is a chemical compound that belongs to the class of benzamidines. It is an organic compound with the molecular formula C7H6ClFN2 and a molecular weight of 168.59 g/mol. 5-chloro-2-fluorobenzamidine is a building block in the synthesis of pharmaceuticals and agrochemicals. It is commonly used as an intermediate in the production of various drugs and pesticides. Its structure contains a benzene ring with a chlorine and fluorine substituent, along with an amidine functional group. 5-chloro-2-fluorobenzamidine is a white crystalline solid that is stable under normal conditions. Its precise applications and properties may vary depending on the specific context of its use in chemical synthesis.

InChI:InChI=1/C7H6ClFN2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,(H3,10,11)

Upstream product

• 57381-34-7 5-chloro-2-fluorobenzonitrile 
• 4039-32-1 lithium hexamethyldisilazane 

Downstream Products

• 859174-12-2 C₁₄H₉ClFN₃O₂ 
• 773139-99-4 C₁₃H₁₀ClFN₂O 
• 674793-54-5 2-(5-chloro-2-fluorophenyl)-5-isopropylpyrimidine-4-one 
• 674793-70-5 2-(5-chloro-2-fluorobenzyl)-5-cyclopropyl-pyrimidone 
• 674793-63-6 2-(5-chloro-2-fluoro)-5-cyclobutylpyrimidine-4-one 
• 859173-98-1 2-(5-chloro-2-fluoro-phenyl)-7-fluoro-3H-pyrido[2,3-d]pyrimidin-4-one 
• 773140-01-5 C₁₃H₁₁ClFN₃O 
• 911700-96-4 6-(5-chloro-2-fluorophenyl)-3-cyclopentyl-1H-pyrimidin-2-one 
• 773140-36-6 2-(5-chloro-2-fluorophenyl)-6,7-dihydrofuro[3,2-d]pyrimidin-4-ol 
• 773140-30-0 2-(5-chloro-2-fluorophenyl)-5,7-dihydrofuro[3,4-d]pyrimidin-4-ol 
• 773140-05-9 C₁₃H₁₁ClFN₃O 
• 773140-40-2 2-(5-chloro-2-fluorophenyl)-5-methyl-6,7-dihydro-5H-cyclopentapyrimidin-4-ol 
• 859173-98-1 2-(5-chloro-2-fluoro-phenyl)-7-fluoro-pyrido[2,3-d]pyrimidin-4-ol 
• 674793-81-8 C₁₆H₁₁ClFN₅O₃ 

Relevant articles and documents

CARBOXAMIDE 4-[(4-PYRIDYL)AMINO]PYRIMIDINES USEFUL AS HCV INHIBITORS

The present invention relates to the use of carboxamide 4-[(4-pyridyl)amino]- pyrimidines as inhibitors of HCV replication as well as their use in pharmaceutical compositions aimed to treat or combat HCV infections.

CARBOXAMIDE INHIBITORS OF TGFB

Certain appropriately substituted forms of pyrimidine having a pyridylamine group at C- 4 of the pyrimidine and an amide group on the pyridine ring are useful in the treatment of conditions associated with excessive TGFB activity.