675587-66-3

Basic information

• Product Name: N,N-dimethyl-2-nitro-5-fluorobenzylamine
• Synonyms: N,N-dimethyl-2-nitro-5-fluorobenzylamine
• CAS NO: 675587-66-3
• Molecular Weight: 198.197
• Mol File: 675587-66-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N-dimethyl-2-nitro-5-fluorobenzylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethyl-2-nitro-5-fluorobenzylamine(675587-66-3)
• EPA Substance Registry System: N,N-dimethyl-2-nitro-5-fluorobenzylamine(675587-66-3)

Safety Data

• Hazardous Substances Data: 675587-66-3(Hazardous Substances Data)

Upstream product

• 456-41-7 1-(Bromomethyl)-3-fluorobenzene 
• 770-18-3 N,N-dimethylaminomethyl-1-fluoro-4-benzene 

Downstream Products

• 675587-83-4 N^ε-t-butyloxycarbonyl-N^α-(2,4-dinitro-5-(dimethylaminomethyl)phenyl)-L-lysine 
• 675587-71-0 N^α-acetyl-O-(2,4-dinitro-5-(dimethylaminomethyl)phenyl)-L-tyrosine 
• 675587-70-9 N^α-acetyl-S-(2,4-dinitro-5-(dimethylaminomethyl)phenyl)-L-cysteine 
• 675587-65-2 N,N-dimethyl-2,4-dinitro-5-fluorobenzylamine 

Relevant articles and documents

Synthesis of N,N-dimethyl-2,4-dinitro-5-fluorobenzylamine and its reactions with amino acids and peptides

A practical synthesis is described for N,N-dimethyl-2,4-dinitro-5- fluorobenzylamine (DMDNFB) and its -d6 analog as an alternative Sanger's reagent (DNFB), for purposes of amino acid derivatization detectable by positive mode electrospray ionization mass spectrometry. DMDNFB is comparable to DNFB in its efficiency to derivatize amino acids and peptides. Various DMDNP (d0/d6) derivatives of (modified) lysine were synthesized to evaluate the potential use of isotope-edited LC-ESI-MS as a tool for structural definition of the posttranslational modification of protein-based lysines.